Results 61 to 70 of about 105,486 (284)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Biological Correlates of Empathy [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2010
Empathy can be defined as the capacity to know emotionally what another is experiencing from within the frame of reference of that other person and the capacity to sample the feelings of another or it can be metaphorized as to put oneself in another’s ...
E. Timucin Oral   +3 more
doaj  

View-Invariant Visuomotor Processing in Computational Mirror Neuron System for Humanoid.

open access: yesPLoS ONE, 2016
Mirror neurons are visuo-motor neurons found in primates and thought to be significant for imitation learning. The proposition that mirror neurons result from associative learning while the neonate observes his own actions has received noteworthy ...
Farhan Dawood, Chu Kiong Loo
doaj   +1 more source

Relationship between activity in human primary motor cortex during action observation and the mirror neuron system [PDF]

open access: yes, 2009
The attenuation of the beta cortical oscillations during action observation has been interpreted as evidence of a mirror neuron system (MNS) in humans.
Baune, B.   +3 more
core  

The Mirror Neuron System [PDF]

open access: yesThe Neuroscientist, 2011
Mirror neurons are a class of visuomotor neurons in the monkey premotor and parietal cortices that discharge during the execution and observation of goal-directed motor acts. They are deemed to be at the basis of primates’ social abilities. In this review, the authors provide a fresh view about two still open questions about mirror neurons.
Casile, Antonino   +2 more
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Towards a Mirror System for the Development of Socially-Mediated Skills [PDF]

open access: yes, 2002
We present a system that attempts to model the functional role of mirror neurons, namely the activation of structures in response to both the observation of a demonstrated task, and its generation.
Hayes, Gillian   +2 more
core   +1 more source

Complementary actions [PDF]

open access: yes, 2015
Complementary colors are color pairs which, when combined in the right proportions, produce white or black. Complementary actions refer here to forms of social interaction wherein individuals adapt their joint actions according to a common aim.
Betti, Sonia, Sartori, Luisa
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Why our brains cherish humanity: Mirror neurons and colamus humanitatem

open access: yesAvances en Psicología Latinoamericana, 2008
Commonsense says we are isolated. After all, our bodies are physically separate. But Seneca’s colamus humanitatem, and John Donne’s observation that “no man is an island” suggests we are neither entirely isolated nor separate.
John R. Skoyles
doaj  

Home - About - Disclaimer - Privacy