Results 41 to 50 of about 13,146 (180)

Mirtazapine Reduces Adipocyte Hypertrophy and Increases Glucose Transporter Expression in Obese Mice

Animals, 2020
Metabolic syndrome is known to engender type 2 diabetes as well as some cardiac, cerebrovascular, and kidney diseases. Mirtazapine—an atypical second-generation antipsychotic drug with less severe side effects than atypical first-generation ...
Ching-Feng Wu, Po-Hsun Hou, Frank Chiahung Mao, Yao-Chi Su, Ching-Yang Wu, Wei-Cheng Yang, Chen-Si Lin, Hsiao-Pei Tsai, Huei-Jyuan Liao, Geng-Ruei Chang   +9 more
doaj   +1 more source

Potential value of slow‐wave sleep in management of chronic insomnia disorder

Sleep Research, EarlyView.
Abstract Chronic insomnia disorder (CID), acknowledged as the most common sleep disorder, has traditionally been diagnosed and managed with a focus on reducing sleep onset latency and extending total sleep duration. However, the critical importance of slow‐wave sleep (SWS), a key indicator of objective sleep quality, has been largely overlooked in ...
Liping Zhang, Qi Wu, Mengmeng Fan, Xianchao Zhao, Changjun Su   +4 more
wiley   +1 more source

The Assessment of Cytotoxicity and Genotoxicity of Mirtazapine in Human Blood Lymphocytes Using Micronucleus Test

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2015
Introduction: Tetracyclic antidepressants-mirtazapin is one of antidepressants drug that exhibits both noradrenergic and serotonergic activity. It is commonly used to treat major depressive disorder.
M Norizadeh tazehkand, M Topaktas
doaj  

Randomized clinical trial: the effects of mirtazapine in functional dyspepsia patients

Therapeutic Advances in Gastroenterology
Background: Functional dyspepsia (FD) is one of the most common gastrointestinal disorders worldwide. Currently, anti-gastric drugs, gastric acid inhibitors, prokinetic drugs, and mucosal protective drugs are widely used in FD patients, however, only a ...
Lina Cao, Gaozhong Li, Jingmei Cao, Fuxin Li, Wei Han   +4 more
doaj   +1 more source

Analysis of In Vitro Mirtazapine Metabolites in Human Liver Microsomes by LC-HRMS

Fayixue Zazhi
ObjectiveTo establish and optimize an in vitro incubation system with human liver microsomes and investigate the in vitro metabolites and possible metabolic pathways of mirtazapine.MethodsThree major metabolites of mirtazapine were selected to optimize ...
ZHANG Ying, ZHANG Wen-fang, XU Duo-qi, QIN Shi-yang, YANG Shi-yun, QIAO Jing   +5 more
doaj   +1 more source

Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study

Addiction, EarlyView.
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock, Krista J. Siefried, Gill Bedi, Steven Albert, Richard O. Day, Nadine Ezard, Margaret Ross, Paul Liknaitzky, Jonathan Brett   +8 more
wiley   +1 more source

Genotoxic and cytotoxic effect of mirtazapine in human peripheral blood lymphocyte: in vitro study

مجله دانشگاه علوم پزشکی گرگان, 2015
Background and Objective: Mirtazapine is a norepinephrine and serotonergic antidepressant that is used in the theraphy of major depressive disorders.
Norizadeh Tazehkand M, Topaktas M, Hajipour O   +2 more
doaj  

Clinical applications of wearable devices for individuals with at‐risk substance use and substance use disorders: A systematic review

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Managing substance use disorders (SUDs) is limited by the lack of longitudinal clinical data during active use and recovery. Wearable devices may help address this gap by capturing physiological and behavioral data in real‐world settings.
Alexandra Sas, Matthew E. Sloan, Yaoyi Xing, Ethan Kim, Dhvani Mehta, Anna Mouzenian, Lena C. Quilty, Jeffrey D. Wardell, Shannon Lange, Daniel Felsky, Victor M. Tang   +10 more
wiley   +1 more source

Adverse event reporting of mirtazapine: A disproportionality analysis of FDA adverse event reporting system (FAERS) database from 2004-2024.

PLoS ONE
BackgroundMirtazapine is a pharmacological agent commonly utilized as a first-line treatment for major depressive disorder, exhibiting both noradrenergic and selective serotonergic activity.
Keying Guo, Haipeng Li, Wei Wang, Ling Cheng, Weina Du, Jing Zhang   +5 more
doaj   +1 more source

Sleep Disorders in Klinefelter Syndrome and Other Sex Chromosome Aneuploidies: A Narrative Review

Andrology, EarlyView.
ABSTRACT Background Sex chromosome aneuploidies (SCAs) are among the most frequent types of chromosomal aneuploidies and include Klinefelter syndrome (47,XXY and higher‐grade variants), 47,XYY syndrome, Turner syndrome (45,X), and trisomy X (47,XXX).
Roberto Paparella, Fabiola Panvino, Ida Pucarelli, Luigi Tarani   +3 more
wiley   +1 more source