Results 81 to 90 of about 12,640 (186)

Deprescription of Psychotropics in Children and Adolescents: Systematic Review of Guidelines and Development of a Deprescribing Algorithm

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background Psychotropics are increasingly prescribed in paediatrics despite limited evidence regarding their benefits and effectiveness. Although deprescribing approaches are established in adults, structured paediatric strategies remain poorly defined.
Paul‐Benoît Fargier, Mark Horowitz, Rodolphe Charles, Valérie Rousselon, Erik Fakra, Marie‐Noëlle Beyens, Marie‐Laure Laroche   +6 more
wiley   +1 more source

Mirtazapine Treatment of a Severe Depressive Episode and Resolution of Elevated Inflammatory Markers

Case Reports in Psychiatry, 2013
Depression has been shown to be associated with systemic inflammatory activity and the mode of action of several antidepressants appears to involve immunomodulation.
Shahzad M. Alikhan, Jessica A. Lee, Luiz Dratcu   +2 more
doaj   +1 more source

Occlusal Dysesthesia: Identifying Knowledge Gaps to Advance Clinical Care

Journal of Oral Rehabilitation, Volume 53, Issue 9, Page 1746-1756, September 2026.
This scoping review highlights major knowledge gaps in the understanding of occlusal dysesthesia, including limited evidence on sensory, psychological and neurobiological mechanisms. Current theories remain largely unverified, underscoring the need for integrated biopsychosocial research to improve diagnosis and patient care.
Sara A. Esmat, Helen He, Iacopo Cioffi
wiley   +1 more source

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2701-2710, August 2026.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen, Anna‐Maija Tolppanen, Valtteri Kaasinen, Marjaana Koponen, Sirpa Hartikainen   +4 more
wiley   +1 more source

A prospective series of acute rivaroxaban overdose, coagulopathy and bleeding complications (ATOM 11)

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2828-2833, August 2026.
Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi, Angela L. Chiew, Keith Harris, Geoffrey K. Isbister   +3 more
wiley   +1 more source

Selective Anti‐Inflammatory Actions of Curcumin on Cytokine Pathways in Major Depressive Disorder

Brain and Behavior, Volume 16, Issue 8, August 2026.
Curcumin partially attenuates IRS/M1/Th1 immune activation in MDD patients ex vivo, but fails to normalize it. Paradoxically, it upregulates immune profiles in healthy controls. Its immunomodulatory effects are state‐dependent, suggesting cautious use in non‐depressed individuals.
Tangcong Chen, Yueyang Luo, Mengqi Niu, Jing Li, Mengdie Li, Yingqian Zhang, Michael Maes   +6 more
wiley   +1 more source

ARFID Triggered by Dysgeusia: A Case Report on Light Therapy, Nutritional Support, and Mirtazapine

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Here, we describe an older man who developed avoidant‐restrictive food intake after an acute onset of dysgeusia that persisted for nearly two years. After initiating a multifactorial treatment approach that included light therapy, nutritional support, and mirtazapine, both the eating disorder and dysgeusia resolved within months.
Aanika Kashyap, Tobi Abibat Saliu, Carrie J. McAdams   +2 more
wiley   +1 more source

Mirtazapine for symptom control in refractory gastroparesis

Drug Design, Development and Therapy, 2017
Mark Malamood,1 Aaron Roberts,2 Rahul Kataria,2 Henry P Parkman,2 Ron Schey2 1Department of Internal Medicine, 2Department of Gastroenterology, Temple University Hospital, Philadelphia, PA, USA Introduction: Gastroparesis symptoms can be severe and ...
Malamood M, Roberts A, Kataria R, Parkman HP, Schey R   +4 more
doaj  

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

Drug Testing and Analysis, Volume 18, Issue 8, Page 1065-1075, August 2026.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis, Helen G. Gika, Georgios Panagiotoglou, Eleni Parlapani, Pavlos Pavlidis, Nikolaos Raikos   +5 more
wiley   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, Volume 47, Issue 8, Page 696-712, August 2026.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source