Results 61 to 70 of about 94,455 (293)

Risk factors for first trimester miscarriage--results from a UK-population-based case-control study.

, 2007
OBJECTIVE: The aim of this study was to examine the association between biological, behavioural and lifestyle risk factors and risk of miscarriage. DESIGN: Population-based case-control study. SETTING: Case-control study nested within a population-based,
S Prior, Prior, S, Simmons, R, R Simmons, N Maconochie, P Doyle, Maconochie, N, Doyle, P   +7 more
core   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Thyroid hormone transport and metabolism are disturbed in the placental villi of miscarriage

Reproductive Biology and Endocrinology, 2023
Background It has been long known that thyroid hormone regulates placental villi development, which is associated with the occurrence of miscarriage. However, whether abnormal thyroid hormone metabolism and transport in placental villi are involved in ...
Zhen Yu, Xinghao Feng, Zhongshan Lin, Xuan Li, Shiyue Su, Huiru Cheng, Yuanyuan Yang, Zhaolian Wei   +7 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Miscarriage in Qatar

, 2020
We often talk in the UK and the western world about the silence and taboos that exist around miscarriage. Opening up the topic and encouraging more conversations are very much part of our work at the M.A..
Kilshaw, Susan
core   +1 more source

The National Women's Health Study: assembly and description of a population-based reproductive cohort. [PDF]

, 2004
BACKGROUND: Miscarriage is a common event but is remarkably difficult to measure in epidemiological studies. Few large-scale population-based studies have been conducted in the UK.
Prior, Susan, Susan Prior, Maconochie, Noreen, Noreen Maconochie, Doyle, Pat, Pat Doyle, Prior Susan, Doyle Pat, Maconochie Noreen   +8 more
core   +2 more sources

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

Advanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang, Weijing Han, Jing Shi, Lisha Wang, Cuijuan Teng, Wei Lin, Jun Fan, Shuang Wang   +7 more
wiley   +1 more source

Factors associated with a positive depression screen after a miscarriage

BMC Psychiatry, 2019
Introduction Miscarriages are a common pregnancy complication and positive depression screen after a miscarriage has been shown to be high in our population.
Steve Kyende Mutiso, Alfred Murage, Abraham Mukaindo Mwaniki   +2 more
doaj   +1 more source

Occupational factors and miscarriages in the US fire service: a cross-sectional analysis of women firefighters

Environmental Health, 2021
Background Evidence from previous studies suggests that women firefighters have greater risk of some adverse reproductive outcomes. The purpose of this study was to investigate whether women firefighters had greater risk of miscarriage compared to non ...
Alesia M. Jung, Sara A. Jahnke, Leslie K. Dennis, Melanie L. Bell, Jefferey L. Burgess, Nattinee Jitnarin, Christopher M. Kaipust, Leslie V. Farland   +7 more
doaj   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source