Results 211 to 220 of about 18,871 (254)

Italian clinical practice GRADE-based guidelines on the diagnosis and treatment of overweight and obesity, endorsed by the Italian National Institute of Health. [PDF]

Eat Weight Disord
Barazzoni R, Buscemi S, Busetto L, Sbraccia P, Bo S, Cereda E, Chianelli M, Chiappetta S, Dalle Grave R, de Caro W, Docimo G, Galloro G, Iannone P, Leonetti F, Lisso F, Manca MC, Medea G, Merli M, Moretti AM, Navarra G, Pagotto U, Paolini B, Papa G, Perrotta N, Pession A, Pilone V, Provenzano V, Rizzo CR, Santomauro M, Segura Garcia C, Spandonaro F, Sukkar S, Todisco P, Tuccinardi D, Vania A, Vanzi V, Williams R, Zani I, Ragghianti B, Silverii GA, Belluzzi A, Masulli M, Redini M, Monami M.   +43 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Monitoring of new psychoactive substances in France: update of addictovigilance data. [PDF]

Eur J Public Health
Autellet A, Lacroix C, Batisse A, Micallef J, Fouilhe N, Le Boisselier R, Peyrière H, Eiden C, French Addictovigilance Network.   +8 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Evaluating Potential Deployment Strategies for Oral Delivery of Vaccines for Cervids. [PDF]

Transbound Emerg Dis
Zimmerling AS, Napper S.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Editorial Board

Integrative Medicine Research, 2015
doaj   +1 more source

Unveiling the toxicological and biochemical evaluation of selected botanical extracts against adult Aphis gossypii (Aphididae: Hemiptera). [PDF]

Sci Rep
Khalaf AF, Hussein K, Ali S, Barakat D, Gad M.   +4 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source