Results 231 to 240 of about 71,839 (258)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Systematic review of prophylactic antibacterial agents for radiation-induced oral mucositis in head and neck cancer. [PDF]

open access: yesSupport Care Cancer
Alicea DS   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Editorial: Endocrine insights into heart disease. [PDF]

open access: yesFront Endocrinol (Lausanne)
Júnior RFR   +3 more
europepmc   +1 more source

Frequencies and causes of pre-analytical errors in a tertiary care hospital laboratory in Saudi Arabia. [PDF]

open access: yesAnn Saudi Med
Alenezy NT   +6 more
europepmc   +1 more source

Drug development in psoriatic arthritis: a trialtrove-based landscape analysis (1999-2025). [PDF]

open access: yesFront Immunol
Wang G   +8 more
europepmc   +1 more source

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