Results 41 to 50 of about 2,712,464 (290)

Moderate alcohol consumption alters both leucocyte gene expression profiles and circulating proteins related to immune response and lipid metabolism in men [PDF]

open access: yes
Moderate alcohol consumption has various effects on immune and inflammatory processes, which could accumulatively modulate chronic disease risk. So far, no comprehensive, integrative profiling has been performed to investigate the effects of longer-term ...
Erk, M.J., van   +4 more
core   +2 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Anti-inflammatory activity of two classical formulations of Laghupanchamula in rats

open access: yesJournal of Ayurveda and Integrative Medicine, 2013
Background: Laghupanchamula denotes combinations of roots of five herbs. However, in Ayurvedic classics besides four common herbs viz. Kantakari, Brihati, Shaliparni, and Prinshniparni, the fifth one is either Gokshura (Laghupanchamula with Gokshura LPG)
Shivani Ghildiyal   +3 more
doaj   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Integration of traditional herbal medicines among the indigenous communities in Thiruvarur District of Tamil Nadu, India

open access: yesJournal of Ayurveda and Integrative Medicine, 2019
Background: Ethnobotanical studies are recognized as effective methods of finding locally important plants for discovery of crude drugs. Siddha medicinal system is prevailed in south Indian states principally in Tamil Nadu and gaining recognition as ...
Jayaraj Krupa   +4 more
doaj  

Male reproductive health and yoga

open access: yesInternational Journal of Yoga, 2013
Now-a-days reproductive health problems along with infertility in male is very often observed. Various Assisted Reproductive Technologies have been introduced to solve the problem, but common people cannot afford the cost of such procedures.
Pallav Sengupta   +2 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Quality of Ayurvedic health care delivery in provinces of India: Lessons from essential drugs availability at State run Ayurveda dispensaries

open access: yesJournal of Ayurveda and Integrative Medicine, 2018
Quality of health care delivery primarily depends upon the availability of resources in terms of manpower, infrastructure and material. Ayurveda has beautifully embodied this concern as chikitsa chatuspad (four essentials of health care delivery). In the
Sanjeev Rastogi
doaj  

Antidiabetic potential of methanolic and flavonoid-rich leaf extracts of Synsepalum dulcificum in type 2 diabetic rats

open access: yesJournal of Ayurveda and Integrative Medicine, 2017
Background: Synsepalum dulcificum is a plant indigenous to West Africa. The fruit is used to modify taste of foods to sweetness. Objectives: This study aims to investigate the antidiabetic potentials of both methanolic and flavonoid-rich leaf extracts of
T.O. Obafemi   +4 more
doaj   +1 more source

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