Results 51 to 60 of about 18,871 (254)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Medical cannabis: From research breakthroughs to shifting public perceptions and ensuring safe use

open access: yesIntegrative Medicine Research
Background: This review aimed to examine the recent breakthroughs in medical cannabis research, explore the shifting public perceptions and the stigma associated with its use and discuss strategies for enhancing the safety of medical cannabis.
Muhammad Kamal Hossain, Han Jung Chae
doaj   +1 more source

Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review

open access: yesIntegrative Medicine Research, 2020
Background: While the world struggles under the coronavirus disease 2019 (COVID-19) pandemic, a variety of antiviral agents and symptomatic treatments are being administered to patients and urgent clinical trials are underway.
Seungwon Kwon   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Yoga as part of sports medicine and rehabilitation

open access: yesInternational Journal of Yoga, 2023
Manjunath Nandi Krishnamurthy
doaj   +1 more source

Effects of Alternative Silvicultural Treatments on Regeneration in the Southern Appalachians

open access: yes, 2008
Harvesting practices in the southern Appalachians have moved away from clearcutting in favor of variable retention harvesting systems. A study was initiated in 1995-8 to investigate the effects of retaining varying numbers of residual trees on ...
Atwood, Chad Judson
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The effect of miniscalpel acupuncture and splint treatment for joint deformity of hand osteoarthritis: a case report

open access: yesIntegrative Medicine Research, 2019
We are reporting the combined therapeutic effect of miniscalpel acupuncture and splint therapy on osteoarthritis of the hand accompanying severe joint deformity.
Kyongha Cho   +2 more
doaj   +1 more source

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