Results 71 to 80 of about 17,985 (268)

Bremsscheiben aus keramischen Verbundwerkstoffen (CMC) fuer Schienenfahrzeuge Abschlussbericht

, 1998
Besides their high weight, conventional cast brake discs have an insufficiant tribological lifetime determining disadvantage. C/C-discs are no alterantive. The goal of the R+D program was to develop and manufacture and to test brake discs made of ceramic
Spoerer, J. (MAN Technologie AG, Karlsfeld (Germany)), Schlenk, L. (Knorr-Bremse Systeme fuer Schienenfahrzeuge GmbH, Muenchen (Germany)), Heidenreich, B. (DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Stuttgart (Germany). Inst. fuer Bauweisen- und Konstruktionsforschung)   +2 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Study on time-based variation of blood circulation index, pulse wave energy, and RAI of healthy adult men after different eating times

Integrative Medicine Research, 2013
Background: The purpose of this study is to examine the effects of different eating times on blood circulation index, pulse wave energy (E), and radial augmentation index (RAI) of healthy adult men.
Gyeong-Cheol Kim, Ki-Young Ji, Yi-Soon Kim, Yi-Sub Kwak   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Role of red grape polyphenols as antidiabetic agents

Integrative Medicine Research, 2014
The worldwide incidence of diabetes mellitus has reached alarming proportions. Persistent hyperglycemia due to impaired insulin activity and/or insulin resistance inversely affects the retina, cerebrovascular system, kidney, peripheral limbs, and other ...
Kanti Bhooshan Pandey, Syed Ibrahim Rizvi   +1 more
doaj   +1 more source

Nichtkonventionelle ohmsche Kontaktsysteme fuer III-V-Halbleiter-Schichtsysteme Schlussbericht

, 1995
Ohmic multilayer contact systems with diffusion barrier layers are investigated which should show improved long-time and/or temperature stability. The investigations concentrate on the system Au/Pt/Ti/ a-WSi_xN_y/Au/Ge/Ni-n-GaAs. Besides that the systems
Nebauer, E., Ferdinand-Braun-Institut fuer Hoechstfrequenztechnik, Berlin (Germany)   +1 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Curcuma xanthorrhiza extract and xanthorrhizol ameliorate cancer-induced adipose wasting in CT26-bearing mice by regulating lipid metabolism and adipose tissue browning

Integrative Medicine Research
Background: Cancer cachexia—characterized by anorexia, body weight loss, skeletal muscle atrophy, and fat loss—affects nearly 80% of cancer patients and accounts for 20% of cancer deaths.
Haeun Kim, Dong-Woo Lee, Jae-Kwan Hwang
doaj   +1 more source

Control of sudden death in cultivated proteas from the Southwest of Western Australia

, 2004
Phytophthora cinnamomi Rands is a common and devastating pathogen of cultivated proteas worldwide. Webb (1997) described a Sudden Death plant disease of proteas in Western Australia (WA) protea plantations.
Dunne, Christopher
core  

Discovery of Pyrano[2,3-c]pyrazole Derivatives as Novel Potential Human Coronavirus Inhibitors: Design, Synthesis, In Silico, In Vitro, and ADME Studies

The SARS-CoV-2 pandemic at the end of 2019 had major worldwide health and economic consequences. Until effective vaccination approaches were created, the healthcare sectors endured a shortage of operative treatments that might prevent the infection’s ...
Abdou K. Allayeh, Mohamed A. Said, Aliaa H. El-boghdady, Mahmoud G. A. Saleh, Mohamed G. Abouelenein, Mohammed T. Abdel-Aal   +5 more
core   +1 more source