Results 91 to 100 of about 17,985 (268)
Weiterentwicklung der Endoskopischen Mikrochirurgie Schlussbericht
, 1993 Since 1980 we worked on the development of Minimal Invasive Surgery. After the introduction of Transanal Endoscopic Microsurgery (TEM) into clinical practise in 1984, as the first endoscopic surgical method, the emphasis of our investigation was put on ...
Mentges, B. +3 more
core
Redress and civil litigation report [PDF]
, 2015 The Royal Commission has examined the extent to which ‘justice for victims’ of institutional child abuse has been, or can be, achieved through previous and current redress processes and civil litigation systems.
Royal Commission into Institutional Responses to Child Sexual Abuse
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Partitioning vegetation response to anthropogenic stress to develop multi-taxa wetland indicators
, 2008 Emergent plants can be suitable indicators of anthropogenic stress in coastal wetlands if their responses to natural environmental variation can be parsed from their responses to human activities in and around wetlands.
Vaccaro, L. +15 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Herstellung supraleitender Schichten mittels Plasmaspritzen und Vakuumspritzen Abschlussbericht
, 1991 Within the scope of this work it is the objective to find working conditions for the plasma spray processing of high temperature superconducting systems La-Sr-Cu-O, Y-Ba-Cu-O and Bi-Sr-Ca-Cu-O.
Lugscheider, E. +1 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
, 2019 Knowledge of carbon (C) and nitrogen (N) dynamics under different irrigation practices in pomegranate orchards is novel and essential to develop sustainable production systems.
Gao, Suduan +4 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source