Results 101 to 110 of about 17,985 (268)

The experience of mesothelioma in Northern England [PDF]

, 2007
Mesothelioma is a potentially preventable fatal disease causing almost 2000 deaths/year in the UK, increasing in incidence, and lacking effective treatments.
Clayson, Helen
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Acupoint selection based on pattern identification results or disease state

Integrative Medicine Research, 2020
Ye-Seul Lee, Yeonhee Ryu, Younbyoung Chae   +2 more
doaj   +1 more source

Elucidação da morfo-histodiferenciação do desenvolvimento de protocormos e estruturas semelhantes a protocormos (ESPs) de espécies de Cattleya Lindl. micropropagadas [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-graduação em Recursos Genéticos Vegetais, Florianópolis, 2013O Bioma Mata Atlântica é um dos ecossistemas mais ricos em diversidade biológica ...
Liz, Rafaela Duarte de
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Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Contribuição de leguminosas arbóreas em consórcio com palma forrageira fertilizada com diferentes estercos [PDF]

, 2018
O consórcio de plantas forrageiras adaptadas às condições edafoclimáticas do Semiárido nordestino brasileiro e a utilização de práticas de manejo adequadas, pode contribuir para melhorar a fertilidade do solo, incrementar a produtividade das culturas e a
MIRANDA, Karina Rodrigues de
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Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A comparison of runoff- and spray-drift-related pesticide contamination in agricultural surface waters : exposure, effects and mitigation

, 2004
Includes bibliographical references.Runoff and spray-drift-related pesticide input are important sources of non pointsource pesticide pollution in surface waters but few studies have directly compared these routes in a risk assessment scenario ...
Dabrowski, James Michael
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Litter dynamics and soil organic matter in Urochloa decumbens Stapf. and Mimosa caesalpiniifolia Benth. under monoculture and silvopastoral system

, 2022
O sistema silvipastoril corresponde a exploração, na mesma área, de árvores, pasto e animais manejados de forma integrada. Objetivou-se avaliar as dinâmicas da serapilheira e da matéria orgânica do solo em urochloa decumbens stapf.
PESSOA, Diana Valadares
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