Results 171 to 180 of about 95,914 (208)

Misfolding

2021
La vita delle piante può essere una soluzione per la vita dell'essere umano?
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Principles of Protein Misfolding

2008
Publisher Summary This chapter discusses the principles of protein misfolding. The process of incorrect folding is called “protein misfolding.” It is associated with a number of pathological states in humans, collectively termed “protein-misfolding diseases.” Among these protein-misfolding diseases, amyloid diseases are characterized by the presence ...
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Protein misfolding in neurodegenerative diseases

Neuropathology and Applied Neurobiology, 2004
A common pathogenic mechanism shared by diverse neurodegenerative disorders, like Alzheimer's disease, Parkinson's disease, Huntington's disease and transmissible spongiform encephalopathies, may be altered protein homeostasis leading to protein misfolding and aggregation of a wide variety of different proteins in the form of insoluble fibrils ...
E I, Agorogiannis, G I, Agorogiannis, A, Papadimitriou, G M, Hadjigeorgiou   +3 more
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Proteomics in protein misfolding diseases

Clinical Chemistry and Laboratory Medicine, 2009
Protein misfolding and deposition as amyloid, with consequent tissue damage, plays a key role in the group of diseases generically termed amyloidoses. In the systemic forms, amyloid deposition is widespread and causes severe dysfunction of vital organs.
STOPPINI, MONICA, LAVATELLI, FRANCESCA, GIORGETTI, SOFIA, MORATTI, REMIGIO, BELLOTTI, VITTORIO, MERLINI, GIAMPAOLO, Laura Obici, Loredana Marchese   +7 more
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Protein degradation, aggregation, and misfolding

Movement Disorders, 2010
AbstractThe cellular surveillance systems guarantee proper removal of altered components from inside cells. Alterations of these systems in neurons have been proposed to be involved in the pathogenesis of different neurodegenerative disorders. In this review, we comment on the advances in our current understanding of how changes in the intracellular ...
Ana Maria, Cuervo, Esther S P, Wong, Marta, Martinez-Vicente   +2 more
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Trashing misfolded membrane proteins

Science, 2014
A branch of the endoplasmic reticulum–associated protein degradation system degrades inner nuclear membrane proteins in yeast.
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Protein Misfolding Cyclic Amplification

2012
Prion diseases are caused by a conformational conversion of the cellular prion protein (PrPC) to a pathological conformer (PrPSc). The “prion-only” hypothesis suggests that PrPSc is the infectious agent that propagates the disease acting as a template for the conversion of PrPC.
Moda F., Pritzkow S., Soto C.
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Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1

Antioxidants, 2022
Vy Ngo, Nadun C Karunatilleke, Wing-Yiu Choy   +2 more
exaly  

Protein-misfolding diseases and chaperone-based therapeutic approaches

FEBS Journal, 2006
Tapan K Chaudhuri, Subhankar Paul
exaly  

Misfolded Proteins

2021
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