Results 111 to 120 of about 1,147,147 (347)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

The Effect of Standardized Photodocumentation on Coding of Pressure Injuries

open access: yes, 2018
Background and Purpose: Pressure injuries (PI) are prevalent and costly for hospitals. Hospitals implement different practices to accurately document PIs ranging from pen and paper to photodocumentation in electronic medical records (EMRs).
Bales, Brandon   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Latent profile analysis of missed nursing care and their predictors among neuro-oncology nurses: a multicenter cross-sectional study

open access: yesBMC Nursing
Purpose To explore potential profile characteristics associated with neuro-oncology nurses’ missed nursing care (MNC) and analyze differences in characteristics of neuro-oncology nurses across these profiles.
Li Ying   +5 more
doaj   +1 more source

Promoting Adherence to Influenza Vaccination Recommendations in Pediatric Practice. [PDF]

open access: yes, 2019
OBJECTIVES: In the United States, nonadherence to seasonal influenza vaccination guidelines for children and adolescents is common and results in unnecessary morbidity and mortality. We conducted a quality improvement project to improve vaccination rates
Cadilla, Adriana   +4 more
core   +1 more source

Maternal near miss as a predictor of nursing diagnoses in critically ill newborns in intensive care

open access: diamond, 2023
Sandra Marisa Pelloso   +6 more
openalex   +2 more sources

Missing Fundamental Nursing Care: What’s the Extent of Missed Oral Care? A Cross-Sectional Study

open access: yesNursing Reports
Background: The Fundamentals of Care framework emphasizes a patient-centered approach that prioritizes the nurse–patient relationship and care environment to meet patients’ basic needs, including oral hygiene. Recognized as crucial for preventing systemic health problems, oral care neglect is a global concern.
Chiara Gallione   +8 more
openaire   +4 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Missed nursing care and related factors: a cross-sectional study

open access: yesBMC Nursing
Background Nurses facing numerous responsibilities in hospitals are often forced to prioritize nursing care. Missed nursing care affects nurses’ ability to effectively manage, oversee, and assess patient care interventions and may contribute to ...
Rahimeh Khajoei   +4 more
doaj   +1 more source

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