Results 101 to 110 of about 1,714,069 (326)

Global sensitivity analysis of randomized trials with nonmonotone missing binary outcomes: Application to studies of substance use disorders [PDF]

open access: green, 2021
Daniel O. Scharfstein   +7 more
openalex   +1 more source

MISSING AT RANDOM ‐ WHAT DOES IT MEAN? [PDF]

open access: yesETS Research Bulletin Series, 1973
ABSTRACTMost articles on missing values assume the missing data are “missing at random” and ignore the process that “caused” the missing values. The condition under which this procedure is justified is explored here: the concept of missing at random is precisely defined, several examples are discussed, and two simple conditions are given which are ...
openaire   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Non-Response in Dynamic Panel Data Models [PDF]

open access: yes
This paper stresses the links that exist between concepts that are used in the theory of model reduction and concepts that arise in the missing data literature.
Cheti Nicoletti
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Exploring a Diagnostic Test for Missingness at Random

open access: yesMathematics
Missing data remain a challenge for researchers and decision-makers due to their impact on analytical accuracy and uncertainty estimation. Many studies on missing data are based on randomness, but randomness itself is problematic. This makes it difficult
Dominick Sutton, Anahid Basiri, Ziqi Li
doaj   +1 more source

Identifying type and determinants of missing items in quality of life questionnaires: Application to the SF-36 French version of the 2003 Decennial Health Survey

open access: yesHealth and Quality of Life Outcomes, 2010
Background Missing items are common in quality of life (QoL) questionnaires and present a challenge for research in this field. The development of sound strategies of replacement and prevention requires accurate knowledge of their type and determinants ...
Coste Joël, Peyre Hugo, Leplège Alain
doaj   +1 more source

Weak consistency of the 1-nearest neighbor measure with applications to missing data

open access: yes, 2019
When data is partially missing at random, imputation and importance weighting are often used to estimate moments of the unobserved population. In this paper, we study 1-nearest neighbor (1NN) importance weighting, which estimates moments by replacing ...
Sharpnack, James
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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