Results 181 to 190 of about 1,667,708 (262)

Missing Data in OHCA Registries: How Multiple Imputation Methods Affect Research Conclusions-Paper II. [PDF]

J Clin Med
Zhan SJ, Saffari SE, Ong MEH, Siddiqui FJ.   +3 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Modeling Individual-Level Uncertainty From Missing Data in Multifactorial Breast Cancer Risk Prediction. [PDF]

JCO Precis Oncol
White BL, Ficorella L, Yang X, Czene K, Eriksson M, Hall P, Archer S, Tischkowitz M, Usher-Smith JA, Easton DF, Antoniou AC.   +10 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Assessing imputation techniques for missing data in small and multicollinear datasets: insights from craniofacial morphometry. [PDF]

BMC Med Res Methodol
Abdullah NA, Hariri F, Hisam MNF, Binti Hassan SF.   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Secure distributed multiple imputation enables missing data inference for private data proprietors. [PDF]

NPJ Digit Med
Smajlović H, Lian Y, Long Q, Numanagić I, Jiang X.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Can discussions with patients and the public clarify missing data mechanisms for digital outcome measures?

Tackney MS, Steele A, Zeissler M, Villar SS, Dearling J, Markham S, Yameen F, (CIG-DO) CIGfDO.   +7 more
europepmc   +1 more source

Recoverability of causal effects under presence of missing data: a longitudinal case study. [PDF]

Biostatistics
Holovchak A, McIlleron H, Denti P, Schomaker M.   +3 more
europepmc   +1 more source