Results 81 to 90 of about 4,243,996 (253)
Journal of the College of Community Physicians, 2018 Using correct methods for prevention, analysis and treatment of missing data is essential in preserving the validity of scientific research. In spite of this, issues related to missing data and non-response bias are found to be inadequately discussed in ...
P. K. B. Mahesh +4 more
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Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
eco: R Package for Ecological Inference in 2x2 Tables
Journal of Statistical Software, 2011 eco is a publicly available R package that implements the Bayesian and likelihood methods proposed in Imai, Lu, and Strauss (2008b) for ecological inference in 2 X 2 tables as well as the method of bounds introduced by (Duncan and Davis 1953).
Kosuke Imai, Ying Lu, Aaron Strauss
doaj
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Stories Across Missing Data Typologies
DIIDThe cases presented here are introduced as representative examples of the typologies outlined in the curatorial framework. The aim of this Stories section is to explore alternative formats that deal with absence of data in different ways and in order to
Simona Colitti
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MIGHT: Statistical Methodology for Missing-Data Imputation in Food Composition Databases
Applied Sciences, 2019 This paper addresses the problem of missing data in food composition databases (FCDBs). The missing data can be either for selected foods or for specific components only. Most often, the problem is solved by human experts subjectively borrowing data from
Gordana Ispirova +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source