Results 81 to 90 of about 1,718,863 (277)
Background Missing items are common in quality of life (QoL) questionnaires and present a challenge for research in this field. The development of sound strategies of replacement and prevention requires accurate knowledge of their type and determinants ...
Coste Joël, Peyre Hugo, Leplège Alain
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Estimation and inference for multi-kink expectile regression with nonignorable dropout
In this paper, we consider parameter estimation, kink points testing and statistical inference for a longitudinal multi-kink expectile regression model with nonignorable dropout.
Dongyu Li, Lei Wang
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Testing Missing at Random Using Instrumental Variables [PDF]
This paper proposes a test for missing at random (MAR). The MAR assumption is shown to be testable given instrumental variables which are independent of response given potential outcomes. A nonparametric testing procedure based on integrated squared distance is proposed. The statistic's asymptotic distribution under the MAR hypothesis is derived.
openaire +6 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Boosting Prediction with Data Missing Not at Random
Boosting has emerged as a useful machine learning technique over the past three decades, attracting increased attention. Most advancements in this area, however, have primarily focused on numerical implementation procedures, often lacking rigorous theoretical justifications.
Yuan Bian, Grace Y. Yi, Wenqing He
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Methylation data imputation performances under different representations and missingness patterns
Background High-throughput technologies enable the cost-effective collection and analysis of DNA methylation data throughout the human genome. This naturally entails missing values management that can complicate the analysis of the data.
Pietro Di Lena +3 more
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An Investigation of Missing Data Methods for Classiffcation Trees [PDF]
There are many different missing data methods used by classification tree algorithms, but few studies have been done comparing their appropriateness and performance.
Ding, Yufeng, Simonoff, Jeffrey S.
core
Score test for missing at random or not
Missing data are frequently encountered in various disciplines and can be divided into three categories: missing completely at random (MCAR), missing at random (MAR) and missing not at random (MNAR). Valid statistical approaches to missing data depend crucially on correct identification of the underlying missingness mechanism.
Wang, Hairu, Lu, Zhiping, Liu, Yukun
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