Results 101 to 110 of about 1,000,074 (295)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Alcohol Use, Abuse, and Dependency in Shanghai [PDF]

, 1992
The use of alcohol for social and ceremonial occasions was recorded in Chinese history as early as 1760 B.C. during the Yin Dynasty (Ci-Hai Encyclopedia, 1979:936).
Fernandez, Marilyn, Liu, William T., Lung, Ching-Tung, Qu, Guang-Ya, Wang, Chang-Hua, Xia, Zheng-Yi, Xu, Chang-Lin, Yu, Elena S.H, Zhang, Ming-Yuan   +8 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A machine learning approach for missing persons cases with high genotyping errors. [PDF]

Front Genet, 2022
Huang M, Liu M, Li H, King J, Smuts A, Budowle B, Ge J.   +6 more
europepmc   +1 more source

Responding to Cross Border Child Trafficking in South Asia: An Analysis of the Feasibility of a Technologically Enabled Missing Child Alert System [PDF]

, 2013
This report examines the feasibility of a technologically enabled system to help respond to the phenomenon of cross-border child trafficking in South Asia, and makes recommendations on how to proceed with a pilot project in the selected areas of ...
Halpin, EF, Lannon, J
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The National Missing and Unidentified Persons System: Genetic Identification of Missing and Unidentified Persons

Forensic Science International: Synergy, 2023
Heather Mckiernan
doaj   +1 more source

Missing (Foreign) Minors in Italy: Lack of Engagement, Institutional Gaps, and Paths Forward

Forensic Sciences
The disappearance of foreign minors in Italy is a long-standing and critically underexamined social phenomenon. Despite alarming figures, public and institutional attention remains episodic and media-driven, often limited to high-profile or criminal ...
Serena De Cunto, Rosa Maria Di Maggio, Pier Matteo Barone   +2 more
doaj   +1 more source

Missing Persons Alert: Finding the Lost "Person" in Patient-Oriented Research. [PDF]

J Patient Exp, 2022
Rao S.
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source