Results 81 to 90 of about 1,000,074 (295)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Potential health impacts of heavy metals on HIV-infected population in USA. [PDF]

open access: yes, 2006
Noninfectious comorbidities such as cardiovascular diseases have become increasingly prevalent and occur earlier in life in persons with HIV infection. Despite the emerging body of literature linking environmental exposures to chronic disease outcomes in
Meliker, Jaymie   +6 more
core   +6 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Conceptualizing Missingness: A Case Study in Rural Mississippi

open access: yesForensic Sciences
Missing persons is an understudied area, especially within forensic anthropology when not associated with cases of mass violence or mass disaster. Affecting more than half a million persons in the United States yearly, missingness has proven to be a ...
Sarajane Smith-Escudero   +3 more
doaj   +1 more source

Development and future perspectives of a humanitarian forensic programme: the committee on missing persons in Cyprus example

open access: yesEgyptian Journal of Forensic Sciences, 2018
Background In 1981, the Committee on Missing Persons in Cyprus (CMP) was established with a clear purpose: to determine the fate of the missing Greek and Turkish Cypriots who disappeared during the periods 1963–64 and 1974.
Maria Ktori, Gülseren Baranhan
doaj   +1 more source

How Many Persons in East Timor Went 'Missing' During the Indonesian Occupation?: Results from Indirect Estimates [PDF]

open access: yes, 2007
Indonesias occupation of East Timor from 1975 to 1999 caused an unknown number of deaths due to violence and starvation. In the first few years alone casualty estimates range from 60,000 (Houk 1978) to over 300,000 (Defert 1992).
Staveteig, S.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Rescuing the Missing: A Study of Prospective Person Memory on Missing Persons [PDF]

open access: yes, 2015
An average of 1,700 missing persons cases are filed everyday in the United States (Federal Bureau of Investigation, 2013). With such a large number of people placed in potential danger, their security is the utmost concern to families, communities, and ...
Spillar, Brandon
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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