Results 61 to 70 of about 183,393 (251)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Predicting the locations of missing persons in China by using NGO data and deep learning techniques
Missing person crimes can seriously affect the well-being of Chinese families, and missing person destination prediction can help to solve this problem.
Anning Dong +9 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Rethinking the Mexican Conflict with a Gender Perspective
This article examines how the expansion of criminal organizations in Mexico affects different forms of violence through a gendered lens. Using an event-study design with data on homicides, feminicides, and missing persons disaggregated by gender, I ...
Juan Carlos Angulo
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Conceptualizing Missingness: A Case Study in Rural Mississippi
Missing persons is an understudied area, especially within forensic anthropology when not associated with cases of mass violence or mass disaster. Affecting more than half a million persons in the United States yearly, missingness has proven to be a ...
Sarajane Smith-Escudero +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Background In 1981, the Committee on Missing Persons in Cyprus (CMP) was established with a clear purpose: to determine the fate of the missing Greek and Turkish Cypriots who disappeared during the periods 1963–64 and 1974.
Maria Ktori, Gülseren Baranhan
doaj +1 more source

