FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Missing persons genetic identification
Zdravniški Vestnik, 2017 This article presents identification of missing persons from badly preserved post-mortem remains using molecular genetics methods. Extremely polymorphic and individually specific genetic markers that enable the identification of missing persons are ...
Matija Bajželj, Irena Zupanič Pajnič
doaj
Area deprivation across the life course and physical capability in mid-life: findings from the 1946 British Birth Cohort [PDF]
, 2013 Physical capability in later life is influenced by factors occurring across the life course, yet exposures to area conditions have only been examined cross-sectionally.
Aucott, Paula +6 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Predicting the locations of missing persons in China by using NGO data and deep learning techniques
International Journal of Digital EarthMissing person crimes can seriously affect the well-being of Chinese families, and missing person destination prediction can help to solve this problem.
Anning Dong +9 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Rethinking the Mexican Conflict with a Gender Perspective
Sobre MéxicoThis article examines how the expansion of criminal organizations in Mexico affects different forms of violence through a gendered lens. Using an event-study design with data on homicides, feminicides, and missing persons disaggregated by gender, I ...
Juan Carlos Angulo
doaj +1 more source
Co-constructing early adolescent education through image-based research : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education at Massey University, Palmerston North [PDF]
, 2006 Professional literature reporting the needs and characteristics, both educational and developmental of early adolescents presents a compelling case that students of this age group are distinct and require the development of a unique educational approach ...
Nelson, Emily Jane
core
Aboriginal status is a prognostic factor for mortality among antiretroviral naïve HIV-positive individuals first initiating HAART [PDF]
, 2006 Affiliation: Mark Daniel: Département de médecine sociale et préventive, Faculté de médecine, Université de Montréal et Centre de recherche du Centre hospitalier de l'Université de MontréalBACKGROUND:Although the impact of Aboriginal status on HIV ...
Bonner, Simon +8 more
core +5 more sources