Results 121 to 130 of about 589,060 (317)
Anaphylaxis, an allergic reaction caused by the massive release of active mediators, can lead to anaphylactic shock (AS), the most severe and potentially life-threatening form of anaphylactic reaction.
Anays Piotin +6 more
doaj +1 more source
Highly water‐soluble dicationic bis(indolium) dyes have been prepared, showing excellent two‐photon absorption and light emission. Their fluorescence behavior discloses an unusual increasing blue shift with increasing solvent polarity, which, in parallel, is beneficial for enhanced detection in biological media.
Carlos Benitez‐Martin +5 more
wiley +1 more source
Cardiac work demands a substantial amount of energy, stored in adenosine triphosphate (ATP), necessary for both contraction and relaxation. To meet these energy requirements, the heart is equipped with an efficient metabolic machinery. Mitochondria, the central organelle in maintaining cardiac function, primarily generate ATP through oxidative ...
openaire +3 more sources
Apoptosis is a coordinated sequence of events culminating in the death of the cell. Many of these biochemical processes are regulated by the mitochondria, including the release of proapoptotic molecules in addition to the caspase-activating cofactor, cytochrome c.
openaire +2 more sources
Mitochondrial aggregation induced by co-expression of Green Fluorescent Protein(GFP)and an antiapoptotic factor Bcl-xL. HeLa cells were co-transfected with cDNA of Bcl-xL and empty control vector(A and B)or GFP(C, D and E). The cells were double-stained with antibody against Bcl-xL(A and C)and a mitochondria specific fluorescent dye, MitoTracker Red(B,
Aokage, Toshiyuki +2 more
openaire +3 more sources
Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive loss of motor neurons, for which current treatment options are limited.
Filomena S. G. Silva +5 more
core +1 more source
Mitochondria-Targeted Chimeric Peptide for Trinitarian Overcoming of Drug Resistance
In this report, an amphiphilic mitochondria-targeted chimeric peptide-based drug delivery system (DDS) was designed to overcome drug resistance. In vitro studies revealed that chimeric peptide could encapsulate doxorubicin (DOX) with high efficacy and ...
Hui-Zhen Jia (1488658) +6 more
core +1 more source
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source
A resazurin-based cell viability assay of mitochondrial DNA-depleted glioma C6ρ0 cells
Objective To establish a method for determining the cell viability of mitochondrial DNA (mtDNA)-depleted C6 cells (C6ρ0) using resazurin as the indicator of redox.
JIN Youcai +4 more
doaj +1 more source
Respiration, activity of oleate oxidation and composition of the total fatty acids of rat liver were investigated in 3'-Me-DAB feeding. 1. Oxidative phosphorylation of rat liver mitochondria decreased temporarily at relatively earlier stages (about 2 to ...
Inaba, Kozo
core +1 more source

