This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan+11 more
wiley +1 more source
Biotechnological approaches and therapeutic potential of mitochondria transfer and transplantation. [PDF]
Kubat GB+9 more
europepmc +1 more source
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang+10 more
wiley +1 more source
Exploring mitochondrial health and transplantation strategies in DCD heart transplantation: a systematic review. [PDF]
Zhang X+8 more
europepmc +1 more source
PHOSPHORYLATIVE AND NONPHOSPHORYLATIVE PATHWAYS OF ELECTRON TRANSFER IN RAT LIVER MITOCHONDRIA
Nathan O. Kaplan+3 more
openalex +1 more source
Efficiency of Oxidative Phosphorylation of Heart Muscle Mitochondria from Digitalized Guinea Pigs [PDF]
Katharine Armstrong Plaut+2 more
openalex +1 more source
To maximize the efficacy of cancer vaccines, adjuvants, collection, lysis, purification, oxidation, loading sites, and sizes, etc., are investigated. The optimized cancer nanovaccines loading whole tumor antigens can cure all or most tumor‐bearing mice in multiple mouse cancer models.
Xiangxiang Xu+13 more
wiley +1 more source
Cigarette Smoke Extract-Induced Necroptosis Causes Mitochondrial DNA Release and Inflammation of Bronchial Epithelial Cells. [PDF]
Mizumura K+8 more
europepmc +1 more source
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang+11 more
wiley +1 more source
Nucleoside diphosphate kinase strongly promotes GDP and ADP metabolism in the cell and affects endogenous proton leak in mitochondria - the kinase is hampered by oxidative phosphorylation inhibitors. [PDF]
Woyda-Ploszczyca AM.
europepmc +1 more source