Results 341 to 350 of about 1,007,169 (424)

Shape Matters: The Utility and Analysis of Altered Yeast Mitochondrial Morphology in Health, Disease, and Biotechnology. [PDF]

Int J Mol Sci
Kichuk T, Avalos JL.
europepmc   +1 more source

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH

Advanced Science, EarlyView.
In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen, Zhaohua Cai, Danrui Xiao, Yiping Shi, Qingqing Xiao, Min Liang, Yangjing Jiang, Yijie Huang, Feng Liang, Guo Zhou, Fei Zhuang, Xia Wang, Huanhuan Huo, Liang Fang, Qin Shao, Ben He   +15 more
wiley   +1 more source

Mitochondria targeted nanoparticles for the treatment of mitochondrial dysfunction-associated brain disorders. [PDF]

Front Bioeng Biotechnol
Buck AC, Maarman GJ, Dube A, Bardien S.
europepmc   +1 more source

Control of Rhizobia Endosymbiosis by Coupling ER Expansion with Enhanced UPR

Advanced Science, EarlyView.
This study reconstructs legume nodule symbiotic cells using three‐dimensional (3D) scanning electron microscopy (SEM) and uncovers that endoplasmic reticulum (ER) expansion and activation of the unfolded protein response (UPR) are two key events in rhizobia accommodation.
Jing Ren, Qi Wang, Xiaxia Zhang, Yongheng Cao, JingXia Wu, Juan Tian, Yanjun Yu, Qingqiu Gong, Zhaosheng Kong   +8 more
wiley   +1 more source

Dysregulation of Mitochondrial in Pulmonary Hypertension-Related Right Ventricular Remodeling: Pathophysiological Features and Targeting Drugs. [PDF]

Rev Cardiovasc Med
Wang Y, Wang Y, Zhang W.
europepmc   +1 more source

Mitochondria

, 1918
Ray C. Friesner
openalex   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

Mitochondrial transplantation for cardioprotection and induction of angiogenesis in ischemic heart disease. [PDF]

Stem Cell Res Ther
Hassanpour P, Sadeghsoltani F, Saghebasl S, Boroumand S, Khanicheragh P, Tafti SHA, Rahbarghazi R, Rahmati M.   +7 more
europepmc   +1 more source

AN EXPERIMENTAL STUDY ON THE COCHLEAR MITOCHONDRIA

, 1956
M. OUSAWA
openalex   +2 more sources

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Advanced Science, EarlyView.
When the normal kidney is subjected to injurious stimuli, it can lead to persistent activation of ATG5. The activation of ATG5 promotes HSP90‐HIF‐1α interaction, resulting in stabilization of HIF‐1α and subsequent activation of glycolysis. Consequently, this process contributes to mitochondrial fission and inflammation, ultimately culminating in kidney
Yan Hu, Jinqing Li, Hui Chen, Yingfeng Shi, Xiaoyan Ma, Yi Wang, Xialin Li, Qin Zhong, Yishu Wang, Daofang Jiang, Shougang Zhuang, Na Liu   +11 more
wiley   +1 more source