Results 301 to 310 of about 712,444 (333)

Cell Culture Substrate Variation Alters Extracellular Vesicle Biogenesis Without Affecting Non‐Coding Repeat RNA Profile

Small, EarlyView.
Cell culture biomechanical conditions influence extracellular vesicles (EVs) production in patient‐derived pancreatic adenocarcinoma (PDAC) cell lines. When grown in 3D conformation and in hydrogels with lower elasticity (0.5kPA), PDAC cells produce higher numbers of EVs, compared with cells grown in 2D on classic cell culture plastic.
Sara I. Veiga, Rebecca L. Porter, Berent Aldikacti, Uma K. Paithankar, Kate Calhoun, Eric Tai, Vishal Thapar, Jillian F. Wise, David T. Ting, Shannon L. Stott   +9 more
wiley   +1 more source

Significance of 80-S ribosomes associated with Neurospora crassa mitochondria [PDF]

, 1976
Bücher, Theodor, Hallermayer, Gerhard, Harmey, Matthew A., Michel, Rainer, Miller, Fritz, Neupert, Walter, Neupert, Walter, Seblald, W., Werner, Sigurd   +8 more
core  

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

PERM1-An Emerging Transcriptional Regulator of Mitochondrial Biogenesis: A Systematic Review. [PDF]

Genes (Basel)
Soares Menezes E, Wu Z, Renwick JRM, Moran-MacDonald A, Gurd BJ.   +4 more
europepmc   +1 more source

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

VIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li, Haonan Zhao, Yibo Li, Qixin Xu, Yang Zi, Tingting Chu, Heran Cao, Shujuan Liu, Zifang Wu, Huanqiang Zhao, Wuzi Dong   +10 more
wiley   +1 more source

Formoterol promotes mitochondrial biogenesis, improves liver regeneration, and suppresses liver injury and inflammation after liver resection in mice with endotoxemia. [PDF]

Int J Physiol Pathophysiol Pharmacol
Richardson AK, Samuvel DJ, Krishnasamy Y, Lemasters JJ, Zhong Z.   +4 more
europepmc   +1 more source

Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations

The Journal of Dermatology, EarlyView.
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley   +1 more source