Results 151 to 160 of about 543,462 (281)

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Drivers of Diagnostic Delay in Mitochondrial Disease: Missed Recognition of Canonical Features. [PDF]

JIMD Rep
Tinker RJ, Jacob N, Syed MG, Kelkar J, Donnelly C, Elsharkawi I, Ganesh J, Gelb BD, Pejaver V, Kozicz T, Morava E.   +10 more
europepmc   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

The Role of Estrogen in Mitochondrial Disease. [PDF]

Cell Mol Neurobiol
Huang X, Pan CH, Yin F, Peng J, Yang L.
europepmc   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Profiles of paediatric patients experiencing stroke-like episodes associated with mitochondrial disease. [PDF]

Front Neurol
Molla GK, Uzun ÖÜ, Agakisili HB, Genç E, Gülten ZA, Yıldırım T, Ersoy AS, Ak B, Gülbahçe A, Yıldız S, Çakar NE, Karaca M, Zübarioğlu T, Hişmi BÖ, Erdöl Ş, Önal H, Kara B, Gökçay GF.   +17 more
europepmc   +1 more source

Mitochondrial genome changes and neurodegenerative diseases

, 2013
Milena Pinto, Carlos T. Moraes
openalex   +1 more source

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease [PDF]

, 2018
David C. Schöndorf, Dina Ivanyuk, Pascale Baden, Álvaro Sánchez-Martínez, Silvia De Cicco, Cong Yu, Ivana Giunta, Lukas Schwarz, Gabriele Di Napoli, Vasiliki Panagiotakopoulou, Sigrun Nestel, Marcus Keatinge, Jan Pruszak, Oliver Bandmann, Bernd Heimrich, Thomas Gasser, Alexander J. Whitworth, Michela Deleidi   +17 more
openalex   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Cardiac magnetic resonance findings in mitochondrial disease: a guide for clinicians. [PDF]

Eur Heart J Imaging Methods Pract
Gray R, Kantartzı V, Lopes LR, Savvatis K, Westwood M.   +4 more
europepmc   +1 more source