Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease [PDF]
Xin Wang+8 more
openalex +1 more source
Photocrosslinkable Kidney Decellularized Extracellular Matrix‐Based Bioink for 3D Bioprinting
A photocrosslinkable bioink is developed from methacrylated decellularized porcine kidney extracellular matrix to create kidney‐specific 3D constructs. This bioink supports high cell viability, promotes multicellular spheroid formation, and enables stable multilayer bioprinting with tunable mechanical properties, providing a versatile platform for ...
Jaemyung Shin+5 more
wiley +1 more source
Taurine supplementation improves physical activity level in a hemodialysis patient with mitochondrial disease: a case report. [PDF]
Yoshida R+21 more
europepmc +1 more source
MITOCHONDRIAL DNA MUTATIONS CAUSE DISEASE, APOPTOSIS, AND PERMEABILITY TRANSITION PORE DYSFUNCTION
Justin L. Mott+2 more
openalex +1 more source
Mitochondrial Diseases ‐ An Expanding Spectrum of Disorders and Affected Genes [PDF]
Jürgen‐Christoph von Kleist-Retzow+3 more
openalex +1 more source
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua+9 more
wiley +1 more source
Family misfortune caused by hereditary bias: a reflection on mitochondrial disease diagnosis in a family. [PDF]
Meng Y+9 more
europepmc +1 more source
Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang+6 more
wiley +1 more source
Phase 2b program with sonlicromanol in patients with mitochondrial disease due to m.3243A>G mutation. [PDF]
Smeitink J+19 more
europepmc +1 more source