MYC-an emerging player in mitochondrial diseases. [PDF]
Front Cell Dev Biol, 2023 Purhonen J, Klefström J, Kallijärvi J.
europepmc +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Clinical Approaches for Mitochondrial Diseases. [PDF]
Cells, 2023 Hong S, Kim S, Kim K, Lee H.
europepmc +1 more source
Biallelic IARS2 mutations presenting as sideroblastic anemia
Haematologica, 2020 Giulia Barcia +15 more
doaj +1 more source
The role of axonal transport and mitochondrial dysfunction in neurodegeneration-focusing on Huntington's disease [PDF]
, 2015 Kisztina Róna-Vörös
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Correction to: 4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson's Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation [PDF]
, 2023 Shubhangini Tiwari +6 more
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Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Mitochondrial DNA haplogroup T is associated with coronary artery disease and diabetic retinopathy: a case control study [PDF]
, 2009 Barbara Kofler +17 more
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NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Mitochondrial dynamics in neurodegenerative diseases [PDF]
, 2018 Bo Su, Xinglong Wang, Ju GAO, Siyue Qin
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