Results 261 to 270 of about 10,435,022 (365)

A decisive technical leap forward for personalized medicine to treat mitochondrial diseases. [PDF]

EMBO Mol Med
Ghifari AS, Ott M.
europepmc   +1 more source

Correction: Current advances in gene therapy of mitochondrial diseases. [PDF]

J Transl Med, 2023
Soldatov VO, Kubekina MV, Skorkina MY, Belykh AE, Egorova TV, Korokin MV, Pokrovskiy MV, Deykin AV, Angelova PR.   +8 more
europepmc   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Open-label pilot study using hydroxytyrosol as dietary supplements in patients with mitochondrial diseases. [PDF]

Orphanet J Rare Dis
Wong TS, Man E, Wong ICK, Li SX, Zhi H, Yeung KMC, Yip KY, Kwong AKY, Belaramani KM, Wong SN, Kwok AMK, Mak M, Chan TCH, Lau PY, Kan YLE, Wong KC, Poon F, Kwok V, Li CYD, Lau P, Lam SM, Chu V, Chan CFG, Fung CW.   +23 more
europepmc   +1 more source

Mitochondrial transplantation as a promising therapy for mitochondrial diseases. [PDF]

Acta Pharm Sin B, 2023
Zhang TG, Miao CY.
europepmc   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation. [PDF]

Brain Pathol, 2023
Miyahara H, Tamai C, Inoue M, Sekiguchi K, Tahara D, Tahara N, Takeda K, Arafuka S, Moriyoshi H, Koizumi R, Akagi A, Riku Y, Sone J, Yoshida M, Ihara K, Iwasaki Y.   +15 more
europepmc   +1 more source

Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients

, 2016
Johannes K. Ehinger, Saori Morota, Magnus J. Hansson, Gesine Paul, Eskil Elmér   +4 more
openalex   +2 more sources

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Correction to: Fetal and obstetrics manifestations of mitochondrial diseases. [PDF]

J Transl Med
Adelizzi A, Giri A, Di Donfrancesco A, Boito S, Prigione A, Bottani E, Bollati V, Tiranti V, Persico N, Brunetti D.   +9 more
europepmc   +1 more source