Results 261 to 270 of about 10,050,443 (381)

What do mitochondrial diseases teach us about normal mitochondrial functions... that we already knew: threshold expression of mitochondrial defects

, 2001
Jean‐Pierre Mazat, Rodrigue Rossignol, Monique Malgat, Christophe Rocher, Benjamin Faustin, Thierry Letellier   +5 more
openalex   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Open-label pilot study using hydroxytyrosol as dietary supplements in patients with mitochondrial diseases. [PDF]

Orphanet J Rare Dis
Wong TS, Man E, Wong ICK, Li SX, Zhi H, Yeung KMC, Yip KY, Kwong AKY, Belaramani KM, Wong SN, Kwok AMK, Mak M, Chan TCH, Lau PY, Kan YLE, Wong KC, Poon F, Kwok V, Li CYD, Lau P, Lam SM, Chu V, Chan CFG, Fung CW.   +23 more
europepmc   +1 more source

Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation. [PDF]

Brain Pathol, 2023
Miyahara H, Tamai C, Inoue M, Sekiguchi K, Tahara D, Tahara N, Takeda K, Arafuka S, Moriyoshi H, Koizumi R, Akagi A, Riku Y, Sone J, Yoshida M, Ihara K, Iwasaki Y.   +15 more
europepmc   +1 more source

Progressive cardiomyopathy as manifestation of mitochondrial disease [PDF]

, 2002
Daneeya Na Nan, Marta Fernández‐Ayala, Jon Infante, P Matorras, Jesús González-Macı́as   +4 more
openalex   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa, Ana Marote, Catarina Barbosa, Jonas Campos, António J. Salgado, Jana B. Nieder   +5 more
wiley   +1 more source

A decisive technical leap forward for personalized medicine to treat mitochondrial diseases. [PDF]

EMBO Mol Med
Ghifari AS, Ott M.
europepmc   +1 more source

Clinical and bi-genomic DNA findings of patients suspected to have mitochondrial diseases. [PDF]

Front Genet, 2023
Gedikbasi A, Toksoy G, Karaca M, Gulec C, Balci MC, Gunes D, Gunes S, Aslanger AD, Unverengil G, Karaman B, Basaran S, Demirkol M, Gokcay GF, Uyguner ZO.   +13 more
europepmc   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Mitochondrial transplantation as a promising therapy for mitochondrial diseases. [PDF]

Acta Pharm Sin B, 2023
Zhang TG, Miao CY.
europepmc   +1 more source