Results 291 to 300 of about 10,050,443 (381)

Mitochondrial Diseases ‐ An Expanding Spectrum of Disorders and Affected Genes [PDF]

, 2003
Jürgen‐Christoph von Kleist-Retzow, U. Schauseil-Zipf, Dietrich Michalk, Wolfram S. Kunz   +3 more
openalex   +1 more source

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

Advanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li, Adriana‐Monica Radu, Azadeh Rezaei, Joel Turner, Kaveh Shakib, Akiko Obata, Toshihiro Kasuga, Gavin Jell   +7 more
wiley   +1 more source

Endocrine Dysfunction in Primary Mitochondrial Diseases.

Endocr Rev
Varughese R, Rahman S.
europepmc   +1 more source

Resolving Phenotypic Variability in Mitochondrial Diseases: Preliminary Findings of a Proteomic Approach. [PDF]

Int J Mol Sci
Cicchinelli M, Primiano G, Servidei S, Ardito M, Percio A, Urbani A, Iavarone F.   +6 more
europepmc   +1 more source

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease [PDF]

, 2003
Xin Wang, Shan Zhu, Martin Drozda, Wenhua Zhang, Irina G. Stavrovskaya, Elena Cattaneo, Robert J. Ferrante, Bruce S. Kristal, Robert M. Friedlander   +8 more
openalex   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Beyond the cochlea: exploring the multifaceted nature of hearing loss in primary mitochondrial diseases. [PDF]

Brain Commun
Koohi N, Holmes S, Male A, Bamiou DE, Dudziec MM, Ramdharry GM, Pizzamiglio C, Hanna MG, Pitceathly RDS, Kaski D.   +9 more
europepmc   +1 more source

Evaluation of cytogenetic and DNA damage in mitochondrial disease patients: effects of coenzyme Q10 therapy [PDF]

, 2003
Lucia Migliore
openalex   +1 more source

Differential Phase Contrast Imaging to Predict MSC Immune Function

Advanced Healthcare Materials, EarlyView.
This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui, Priyanka Priyadarshani, Adrian Ross Liversage, Carlos Munoz, Steven Stice, Luke J. Mortensen   +5 more
wiley   +1 more source

Photocrosslinkable Kidney Decellularized Extracellular Matrix‐Based Bioink for 3D Bioprinting

Advanced Healthcare Materials, EarlyView.
A photocrosslinkable bioink is developed from methacrylated decellularized porcine kidney extracellular matrix to create kidney‐specific 3D constructs. This bioink supports high cell viability, promotes multicellular spheroid formation, and enables stable multilayer bioprinting with tunable mechanical properties, providing a versatile platform for ...
Jaemyung Shin, Nima Tabatabaei Rezaei, Subin Choi, Zhangkang Li, Deok‐Ho Kim, Keekyoung Kim   +5 more
wiley   +1 more source