Results 21 to 30 of about 920,301 (294)

A rapid and efficient method for enriching mitochondrial DNA from plants

open access: yesMitochondrial DNA. Part B. Resources, 2018
Current mitochondrial purification techniques are tedious and protracted due to their emphasis on recovering physiologically active mitochondria. However, for studies that are exclusively interested in isolating mitochondrial DNA (mtDNA) for applications
Mackenzie M. Strehle   +2 more
doaj   +1 more source

The Role of Mitochondria in Human Fertility and Early Embryo Development: What Can We Learn for Clinical Application of Assessing and Improving Mitochondrial DNA?

open access: yesCells, 2022
Mitochondria are well known as ‘the powerhouses of the cell’. Indeed, their major role is cellular energy production driven by both mitochondrial and nuclear DNA.
Amira Podolak   +2 more
doaj   +1 more source

Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA [PDF]

open access: yes, 1994
Mitochondrial heat shock protein 70 (mt-Hsp70) has been shown to play an important role in facilitating import into, as well as folding and assembly of nuclear-encoded proteins in the mitochondrial matrix.
Craig, Elisabeth A.   +3 more
core   +4 more sources

A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress. [PDF]

open access: yes, 2018
BACKGROUND:Chronic life stress, such as the stress of caregiving, can promote pathophysiology, but the underlying cellular mechanisms are not well understood.
Aschbacher, Kirstin   +7 more
core   +1 more source

Structure–Function Analysis Reveals the Singularity of Plant Mitochondrial DNA Replication Components: A Mosaic and Redundant System

open access: yesPlants, 2019
Plants are sessile organisms, and their DNA is particularly exposed to damaging agents. The integrity of plant mitochondrial and plastid genomes is necessary for cell survival.
Luis Gabriel Brieba
doaj   +1 more source

Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae [PDF]

open access: yes, 2019
Sterols are essential lipids, involved in many biological processes. In Saccharomyces cerevisiae, the enzymes of the ergosterol biosynthetic pathway (Erg proteins) are localized in different cellular compartments.
Balliano, Gianni   +6 more
core   +2 more sources

Determination of Mitochondrial DNA Upon Drug Treatment

open access: yesBio-Protocol, 2015
Drug-induced mitochondrial injury can be caused by many different mechanisms including inhibition of mitochondrial DNA replication, transcription, translation, and altered protein function.
Michel Perron, Joy Feng
doaj   +1 more source

A new method for long-read sequencing of animal mitochondrial genomes: application to the identification of equine mitochondrial DNA variants

open access: yesBMC Genomics, 2020
Background Mitochondrial DNA is remarkably polymorphic. This is why animal geneticists survey mitochondrial genomes variations for fundamental and applied purposes.
Sophie Dhorne-Pollet   +2 more
doaj   +1 more source

Extensive Structural Variations Between Mitochondrial Genomes of CMS and Normal Peppers (Capsicum Annuum L.) Revealed by Complete Nucleotide Sequencing [PDF]

open access: yes, 2014
Cytoplasmic male sterility (CMS) is an inability to produce functional pollen that is caused by mutation of the mitochondrial genome. Comparative analyses of mitochondrial genomes of lines with and without CMS in several species have revealed structural ...
Choi, Yoomi   +4 more
core   +2 more sources

MitoNeoD:a mitochondria-targeted superoxide probe [PDF]

open access: yes, 2017
Mitochondrial superoxide (O2⋅−) underlies much oxidative damage and redox signaling. Fluorescent probes can detect O2⋅−, but are of limited applicability in vivo, while in cells their usefulness is constrained by side reactions and DNA intercalation.
Anderson, Robert F.   +19 more
core   +5 more sources

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