Results 171 to 180 of about 664,986 (295)

Autophagy gene expression in skeletal muscle of older individuals is associated with physical performance, muscle volume and mitochondrial function in the study of muscle, mobility and aging ( SOMMA ) [PDF]

Paul M. Coen, Zhiguang Huo, Gregory J. Tranah, Haley N. Barnes, Xiping Zhang, Christopher A. Wolff, Kevin G. Wu, Peggy M. Cawthon, Russell T. Hepple, Frederico G. S. Toledo, Daniel S. Evans, Olaya Santiago‐Fernández, Ana María Cuervo, Stephen B. Kritchevsky, Anne B. Newman, Steven R. Cummings, Karyn A. Esser   +16 more
openalex   +1 more source

Investigating the impact of physical activity on mitochondrial function in Parkinson’s disease (PARKEX): Study protocol for A randomized controlled clinical trial

, 2023
Juan Carlos Magaña, Cláudia M. Deus, Laura Baldellou, Mercè Avellanet, Elvira Gea-Rodríguez, Silvia Enríquez-Calzada, Ariadna Laguna, Marta Martínez‐Vicente, Jorge Hernández‐Vara, Maria Giné‐Garriga, Susana P. Pereira, Joel Montané   +11 more
openalex   +1 more source

XPNPEP2 regulates angiogenesis via modulation of mitochondrial function through SLC25A6. [PDF]

Front Cell Dev Biol
Yang C, Lu Y, Xia Y, Wang B, Xu J, Zhang Y, Yan J, Liu M, Chen T, Zhao X, Cang X, Mao J, Jiang P.   +12 more
europepmc   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient-Derived Brain Organoids. [PDF]

Adv Sci (Weinh)
Zhang Z, Yangzom T, Lu N, Deng S, Xiao X, Yang G, Liang KX.   +6 more
europepmc   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

The application of nanotechnology in regulating mitochondrial function in tumor microenvironment for cancer therapy. [PDF]

Theranostics
Wang D, Yuan M, Liu J, Zhao M, Fang T.
europepmc   +1 more source

Fluorescent Nanodiamonds Based Theranostic Platform for pH‐Sensitive Drug Delivery and Quantum Sensing

Advanced Functional Materials, EarlyView.
A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu, Siyu Fan, Yue Zhang, Willem Woudstra, Thomas Mulder, Laurens Boscher Navarro, Jur van Dijken, Katja Loos, Romana Schirhagl   +8 more
wiley   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Elamipretide Improves Mitochondrial Function in Mitochondrial Trifunctional Protein-Deficient Mice and Human Fibroblasts. [PDF]

J Inherit Metab Dis
Vieira Neto E, Wang M, Szuminsky AJ, Ferraro L, Basu S, Zhao X, Karunanidhi A, Wang Y, Vockley J.   +8 more
europepmc   +1 more source