Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague +8 more
wiley +1 more source
Dysregulation of Mitochondrial Function in Cancer Cells. [PDF]
Awad AMAM, Abdul Karim N.
europepmc +1 more source
Function of the maize mitochondrial chaperonin hsp60: specific association between hsp60 and newly synthesized F1-ATPase alpha subunits. [PDF]
Tottempudi K. Prasad +2 more
openalex +1 more source
CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani +11 more
wiley +1 more source
Trivalent and Pentavalent Antimonials Impair Cardiac Mitochondrial Function in Mice. [PDF]
Souza IIA +7 more
europepmc +1 more source
Effect of Diet and Starvation on Hepatic Mitochondrial Function in the Rat
Linda J. Brady, Charles L. Hoppel
openalex +1 more source
A yeast mitochondrial leader peptide functions in vivo as a dual targeting signal for both chloroplasts and mitochondria. [PDF]
Jianguo Huang +3 more
openalex +1 more source
Moyamoya Disease and the Risk of Parkinson's Disease
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo +9 more
wiley +1 more source
Detection of changes in mitochondrial function during apoptosis by simultaneous staining with multiple fluorescent dyes and correlated multiparameter flow cytometry [PDF]
Martin Poot, Robert H. Pierce
openalex +2 more sources
Glucosylsphingosine affects mitochondrial function in a neuronal cell model. [PDF]
Nikolaenko V +6 more
europepmc +1 more source

