Results 171 to 180 of about 44,988 (276)

Muscle fibre type shift in COPD: Adaptive, maladaptive or a bit of both?

Experimental Physiology, EarlyView.
Jacob Peter Hartmann, Hannah G. Caldwell, Ulrik Winning Iepsen   +2 more
wiley   +1 more source

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

Cancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source

Clinical and pathological characteristics of mitochondrial myopathy and the screening value of simplified serum lactic acid exercise test

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Objective To analyze clinical and pathological characteristics of mitochondrial myopathy (MM) in 15 patients, and to study the value of simplified serum lactic acid exercise test in the screening of mitochondrial myopathy.
Xiao-fen ZHU, Ji DING, Xiao-qi ZHU, Yuan-yuan LI, Ai-lian DU   +4 more
doaj  

Biallelic Variants in ENDOG Associated with Mitochondrial Myopathy and Multiple mtDNA Deletions. [PDF]

Cells, 2022
Nasca A, Legati A, Meneri M, Ermert ME, Frascarelli C, Zanetti N, Garbellini M, Comi GP, Catania A, Lamperti C, Ronchi D, Ghezzi D.   +11 more
europepmc   +1 more source

Mitochondrial transplantation as a novel therapeutic approach in idiopathic inflammatory myopathy [PDF]

Jeong Yeon Kim, Young Cheol Kang, Min Jung Kim, Seon Uk Kim, Hae Rim Kang, Jeong Seon Yeo, Yujin Kim, Shin-Hye Yu, Byeongwook Song, Jung Wook Hwang, Yun‐Sang Lee, Jung Woo Byun, Dae‐Hyun Yoo, Hyun Sook Kim, Kyuboem Han, Chun‐Hyung Kim, Eun Young Lee   +16 more
openalex   +1 more source

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar, Triveni Kodi, Adarsh Gopinathan, Bharath Harohalli Byregowda, Krishnadas Nandakumar, Anoop Kishore   +5 more
wiley   +1 more source

Depletion of plasma thymidine results in growth retardation and mitochondrial myopathy in mice overexpressing human thymidine phosphorylase. [PDF]

J Biol Chem, 2023
Harada N, Nagasaki H, Yamamoto H, Matsubara K, Suzuki T, Gomori A, Yokogawa T, Matsuo K, Miyadera K.   +8 more
europepmc   +1 more source

Effects of OXPHOS complex deficiencies and ESA dysfunction in working intact skeletal muscle: implications for mitochondrial myopathies

, 2015
Bernard Korzeniewski
openalex   +2 more sources

Molecular Mechanisms and Therapeutic Potential of DJ‐1 in Skeletal Muscle Homeostasis and Disease

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
DJ‐1 protein functions as a redox‐sensing guardian in skeletal muscle by coordinating antioxidant defense, mitochondrial homeostasis, metabolic adaptation, and anti‐atrophy signaling. Enhancing its function holds promise as a potential therapeutic strategy for muscle atrophy, ALS, and metabolic myopathies.
Yue Zhang, Menghuan Li, Xiaojing Xie, Baokai Tian, Zhenwei Bao, Xuejie Yi   +5 more
wiley   +1 more source

Diagnosis and treatment of mitochondrial myopathies [PDF]

, 2011
Gerald Pfeffer, Patrick F. Chinnery
openalex   +1 more source