Results 101 to 110 of about 802,688 (257)

Precursor proteins in transit through mitochondrial contact sites interact with hsp70 in the matrix [PDF]

open access: yes, 1990
We previously reported that hsp70 in the mitochondrial matrix (mt-hsp70 = Ssc1p) is required for import of precursor proteins destined for the matrix or intermembrane space.
Chamberlain   +40 more
core   +1 more source

Disorders of mitochondrial protein synthesis [PDF]

open access: yesHuman Molecular Genetics, 2003
Mitochondrial tRNA gene mutations, including heteroplasmic deletions that eliminate one or more tRNAs, as well as point mutations that may be either hetero- or homoplasmic, are associated with a wide spectrum of human diseases. These range from rare syndromic disorders to cases of commoner conditions such as sensorineural deafness or cardiomyopathy ...
openaire   +3 more sources

Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation.

open access: yesPLoS Biology, 2013
It has been reported that feeding mice resveratrol activates AMPK and SIRT1 in skeletal muscle leading to deacetylation and activation of PGC-1α, increased mitochondrial biogenesis, and improved running endurance.
Kazuhiko Higashida   +5 more
doaj   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

open access: yes, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Neupert, Walter   +4 more
core  

Alterations in the mitochondrial proteome of neuroblastoma cells 2 in response to complex 1 inhibition [PDF]

open access: yes, 2011
Increasing evidence points to mitochondrial dysfunction in Parkinson's disease (PD) associated with complex I dysfunction, but the exact pathways which lead to cell death have not been resolved.
Billett, EE   +3 more
core   +1 more source

Regulation of Mitochondrial Dynamics by Proteolytic Processing and Protein Turnover

open access: yesAntioxidants, 2018
The mitochondrial network is a dynamic organization within eukaryotic cells that participates in a variety of essential cellular processes, such as adenosine triphosphate (ATP) synthesis, central metabolism, apoptosis and inflammation.
Sumaira Ali, Gavin P. McStay
doaj   +1 more source

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