Results 171 to 180 of about 914,673 (333)
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Mitochondrial Proteins as Source of Cancer Neoantigens. [PDF]
Int J Mol Sci, 2022 Prota G, Lechuga-Vieco AV, De Libero G.
europepmc +1 more source
Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity [PDF]
, 2021 Dipsikha Biswas +9 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
Mitochondrial protein targeting signals [PDF]
Biochemical Society Transactions, 1988 G A, Reid, M E, Walker
openaire +2 more sources
Long-lived mitochondrial proteins and why they exist. [PDF]
Trends Cell Biol, 2022 Bomba-Warczak E, Savas JN.
europepmc +1 more source
Synthesis and assembly of mitochondrial proteins [PDF]
, 1988 Das, Rathindra C. +3 more
core +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins. [PDF]
Antioxidants (Basel), 2022 Miller CE +10 more
europepmc +1 more source