Results 181 to 190 of about 2,483,935 (295)

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement. [PDF]

Nat Commun
Vats S, Dionisio P, Lemercier Q, Pineau R, Therreau L, Lipecka J, Cholley B, Moog JB, Wojnacki J, Keime C, Zala D, Bun P, Freire S, Domingues N, Danglot L, Guerrera IC, Delevoye C, Chevet E, Raimundo N, Galli T.   +19 more
europepmc   +1 more source

A novel deep learning-assisted hybrid network for plasmodium falciparum parasite mitochondrial proteins classification. [PDF]

PLoS One, 2022
Alsanousi WA, Ahmed NY, Hamid EM, Elbashir MK, Musa MEM, Wang J, Khan N, Afnan.   +7 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Mitochondrial proteins as biomarkers of cellular senescence and age-associated diseases. [PDF]

Aging (Albany NY)
Panfilova A, Zubareva T, Mironova E, Mazzoccoli G, Marasco MGP, Balazovskaia S, Yablonsky P, Kvetnoy I.   +7 more
europepmc   +1 more source

Genetic screen identifies non-mitochondrial proteins involved in the maintenance of mitochondrial homeostasis. [PDF]

MicroPubl Biol, 2022
Rolland S, Conradt B.
europepmc   +1 more source

Synthesis and intracellular transport of mitochondrial proteins [PDF]

, 1985
Walter Neupert, Harmey, Matthew A., Neupert, Walter, Martonosi, Anthony N., Matthew A. Harmey   +4 more
core   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

Advanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi, Yukari Muramatsu, Akihiro Nakaya, Yuji Maruo, Rick C. Tsai, Masashi Suganuma, Hisashi Ohta, Atsuhito Takeda, Hideyoshi Harashima, Yuma Yamada   +9 more
wiley   +1 more source

A novel connection between Trypanosoma brucei mitochondrial proteins TbTim17 and TbTRAP1 is discovered using Biotinylation Identification (BioID). [PDF]

J Biol Chem, 2022
Soto-Gonzalez F, Tripathi A, Cooley A, Paromov V, Rana T, Chaudhuri M.   +5 more
europepmc   +1 more source