Results 181 to 190 of about 910,991 (300)

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Genetic screen identifies non-mitochondrial proteins involved in the maintenance of mitochondrial homeostasis. [PDF]

MicroPubl Biol, 2022
Rolland S, Conradt B.
europepmc   +1 more source

Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges

Advanced Functional Materials, EarlyView.
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley   +1 more source

A novel connection between Trypanosoma brucei mitochondrial proteins TbTim17 and TbTRAP1 is discovered using Biotinylation Identification (BioID). [PDF]

J Biol Chem, 2022
Soto-Gonzalez F, Tripathi A, Cooley A, Paromov V, Rana T, Chaudhuri M.   +5 more
europepmc   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source

Mitochondrial proteins and congenital birth defect risk: a mendelian randomization study. [PDF]

BMC Pregnancy Childbirth
Li XY, Li DT, Li YY, Xu ZC, Zhang Q, Chen X, Xu F, Zhang RH.   +7 more
europepmc   +1 more source

A Prioritized and Validated Resource of Mitochondrial Proteins in Plasmodium Identifies Unique Biology. [PDF]

mSphere, 2021
van Esveld SL, Meerstein-Kessel L, Boshoven C, Baaij JF, Barylyuk K, Coolen JPM, van Strien J, Duim RAJ, Dutilh BE, Garza DR, Letterie M, Proellochs NI, de Ridder MN, Venkatasubramanian PB, de Vries LE, Waller RF, Kooij TWA, Huynen MA.   +17 more
europepmc   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Exploring genetic associations and drug targets for mitochondrial proteins and schizophrenia risk. [PDF]

Schizophrenia (Heidelb)
Sun W, Sun P, Li J, Yang Q, Tian Q, Yuan S, Zhang X, Chen P, Li C, Zhang X.   +9 more
europepmc   +1 more source

Neuralized-like protein 4 (NEURL4) mediates ADP-ribosylation of mitochondrial proteins. [PDF]

J Cell Biol, 2022
Cardamone MD, Gao Y, Kwan J, Hayashi V, Sheeran M, Xu J, English J, Orofino J, Emili A, Perissi V.   +9 more
europepmc   +1 more source