Results 41 to 50 of about 808,587 (145)

Structural Snapshots of F1‐ATPase Catalysis in Drug Resistant Acinetobacter baumannii Reveal Novel Therapeutic Targets

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
The different Abε's CTD states act as different “gears” to modulate ATP synthesis/hydrolysis, allowing the cell to adapt to environmental changes. Under unfavorable conditions, ATP synthesis is maintained while hydrolysis is inhibited through extended εCTD (low‐gear mode).
Khoa C. M. Le   +4 more
wiley   +1 more source

The complete mitochondrial genome of Yarrowia lipolytica [PDF]

open access: yes, 2001
We here report the complete nucleotide sequence of the 47.9 kb mitochondrial (mt) genome from the obligate aerobic yeast Yarrowia lipolytica.
Casaregola, Serge   +8 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, Volume 600, Issue 20, Page 2981-3008, October 2026.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

I hereby declare that the work presented in this document is based on research carried out by me, and that no part has previously been submitted for a degree in this or any other university [PDF]

open access: yes, 1995
Inhibitors of known transport processes, in conjunction with ion substitution were used in biochemical, physiological and microelectrode studies to investigate the mechanisms underlying ion and fluid secretion across the Malpighian tubules of Locusta ...
Marshall, Sarah Louise
core  

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su   +9 more
wiley   +1 more source

Rev‐erb‐α in Skeletal Muscle Adaptation: Integrating Circadian Control Mechanisms and Exercise Dynamic Responses

open access: yesJournal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Circadian rhythms orchestrate a host of biological processes in a time‐dependent manner to maintain homeostasis in response to exercise. Within this framework, Rev‐erb‐α, an intracellular nuclear receptor and transcriptional regulator, transcends its role in circadian rhythms to drive myogenesis, muscle remodeling, primary metabolism, and ...
Ivo Vieira de Sousa Neto   +7 more
wiley   +1 more source

ATP6V0D2 Promotes Atherosclerosis‐Associated Vascular Smooth Muscle Cell Dysfunction by Modulating Ferroptosis‐Related Signaling

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 10, October 2026.
This study identifies upregulated ATP6V0D2 as a key regulator of ox‐LDL‐induced pathological changes in human vascular smooth muscle cells. ATP6V0D2 knockdown alleviates atherosclerosis‐related dysfunction by suppressing ferroptosis, providing a potential target for atherosclerosis.
Chaohui Zhang   +6 more
wiley   +1 more source

Proteinaceous receptors for the import of mitochondrial precursor proteins [PDF]

open access: yes, 1984
Mild trypsin treatment of isolated Neurospora mitochondria strongly inhibits their ability to bind and import the precursors of several mitochondrial proteins.
Schleyer, Manfred   +2 more
core   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng   +4 more
wiley   +1 more source

Three proton-pumping ATPases in yeast.

open access: yes, 1986
Yeast cells contain three distinct proton-pumping ATPases associated with the mitochondrial, vacuolar or plasma membranes.
Boutry, Marc, Goffeau, André
core  

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