Results 221 to 230 of about 367,263 (290)

Architectural principles of the ribosomal large subunit revealed by A-helix spatial organization. [PDF]

Sci Rep
Lan YS, Tu JH, Wang YC, Hsiao C.
europepmc   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

Mitochondrion-targeted therapies for diabetic wound healing: from mechanism to therapeutic opportunity. [PDF]

Burns Trauma
Wu Q, Xiao F, Wang H, Xiong Y, Mi B.
europepmc   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

A rule-based simulation model illuminates the role of asymmetric mitochondrial fission on beta-cell health. [PDF]

NPJ Syst Biol Appl
Henning P, Schultz J, Baltrusch S, Uhrmacher AM.   +3 more
europepmc   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Integrative analysis of CAM photosynthesis reveals its impact on primary metabolism in Yucca. [PDF]

J Exp Bot
Wickell D, Field R, Weitz K, Chu R, Trejo J, Tolic N, Munoz NM, Hundley H, Savage E, Lipzen A, Leebens-Mack J, Heyduk K.   +11 more
europepmc   +1 more source

tRNA modification in the mitochondrion

Reactome - a curated knowledgebase of biological pathways, 2015
openaire   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

Ultrastructural characteristics of the trabecular meshwork in primary open-angle glaucoma versus chronic angle-closure glaucoma: a comparative study. [PDF]

BMC Ophthalmol
Liang Z, Wu K, Lu Y, Yang F, Lv K, Yan H, Hu Y, Wu H.   +7 more
europepmc   +1 more source