Results 51 to 60 of about 354,115 (299)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural features of a mitochondrion captured spanning 2 varicosities (“Var”). [PDF]
, 2018 (A) A 10-nm slice through a 3D tomographic reconstruction showing a mitochondrion spanning 2 closely spaced varicosities connected by a short (approximately 100 nm) axon segment. An expanded region of the red box shown in (A) reveals the tubulated nature
Tara D. Fischer (5753723) +3 more
core +1 more source
Frontiers in Physiology, 2018 Retinitis pigmentosa (RP) is one of the most common clinical subtypes of retinal degeneration (RD), and it is a neurodegenerative disease that could cause complete blindness in humans because it ultimately affects the photoreceptors viability.
Mari-Luz Moreno +5 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Localization of riboproteins in a trypanosomatid mitochondrion [PDF]
, 2000 There is growing evidence in support of mitochondrial translation in trypanosomes but mitoribosomes have never been characterized or localized in these parasites.
Ivor Tittawella +3 more
core +1 more source
Characterization of a Novel Fis1 Interactor Required for Peripheral Distribution of the Mitochondrion of Toxoplasma Gondii [PDF]
, 2021 Indiana University-Purdue University Indianapolis (IUPUI)Toxoplasma’s singular mitochondrion is extremely dynamic and undergoes morphological changes throughout the parasite’s life cycle.
Jacobs, Kylie
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Cell Biology of the Mitochondrion [PDF]
Genetics, 2017 AbstractMitochondria are best known for harboring pathways involved in ATP synthesis through the tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding these roles were made with Caenorhabditiselegans mutants affecting key components of the metabolic pathways.
van der Bliek, Alexander M +2 more
openaire +4 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
The HA89 fertile line complete mitochondrion sequence [PDF]
, 2018 The complete mitochondrion sequence of the HA89 fertile line of sunflower (Helianthus annuus L) in FASTA format.
Tatiana Tatarinova (159755) +1 more
core +1 more source