Results 191 to 200 of about 520,457 (360)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Host Protein Kinase C⍺: The novel Mitogen Activated Protein Kinase (MAPK) specific scaffold regulating nuclear export of influenza virus ribonucleoprotein complexes. [PDF]

PLoS Pathog
Das Jana I, Dey S, Si M, Roy A, Mondal A.   +4 more
europepmc   +1 more source

Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway

, 2001
Gerard S. De Zutter, Roger J. Davis
openalex   +1 more source

Jingui Shenqi pill ( ) treats cardiorenal syndrome by inhibiting mitogen-activated protein kinase signaling pathway and reducing inflammatory response. [PDF]

J Tradit Chin Med
Shuyan H, Xinyue D, Hui Z, Zongjun L, Yuling L, Lina X.   +5 more
europepmc   +1 more source

LY303511 Enhances TRAIL Sensitivity of SHEP-1 Neuroblastoma Cells via Hydrogen Peroxide–Mediated Mitogen-Activated Protein Kinase Activation and Up-regulation of Death Receptors

, 2009
Kirthan Shenoy, Yongfei Wu, Shazib Pervaiz   +2 more
openalex   +2 more sources

Dual-specificity mitogen-activated protein kinase kinases can use ADP to phosphorylate MAP kinases invitro. [PDF]

J Biol Chem
Juyoux P, von Velsen J, Pellegrini E, Bowler MW.   +3 more
europepmc   +1 more source

Involvement of mitogen-activated protein kinase activation in the signal-transduction pathways of the soya bean oxidative burst [PDF]

, 2001
Ann Taylor, Jitae Kim, Philip S. Low
openalex   +1 more source

Mitogen-Activated Protein Kinases [PDF]

, 2010
Eric Ho, Jim Woodgett
openaire   +1 more source

Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase).

EMBO Journal, 1991
D. Payne, Anthony, J. Rossomando, P. Martino, A. Erickson, J. Her, J. Shabanowitz, D. Hunt, M. J. Weber, T. Sturgill   +9 more
semanticscholar   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source