Results 191 to 200 of about 4,675,421 (262)

P2X7 receptors promote atrial remodeling and atrial fibrillation susceptibility via reactive oxygen species-mediated mitogen-activated protein kinase signaling activation. [PDF]

J Cell Commun Signal
Zhang L, Zhu Y, Gu X.
europepmc   +1 more source

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

Food Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang, Caiyun Feng, Mengyao Zhu, Xu Guo, Yingying Chen, Wenwen Hu, Fei Dong, Jinyue Sun, Chao Liu   +8 more
wiley   +1 more source

<i>In silico</i> study of <i>Spatholobus littoralis</i> Hassk. wood compounds on p38 mitogen-activated protein kinase receptor. [PDF]

J Adv Pharm Technol Res
Ervina M, Firdaus MA, Caroline, Siswandono, Wiranata BI.   +4 more
europepmc   +1 more source

Metabolite Profiles and Antioxidant Activity of Dendrobium catenatum Under Simulated Wild Cultivation

Food Safety and Health, EarlyView.
Dendrobium catenatum grown under simulated wild cultivation showed significantly higher flavonoids and stilbenes, leading to enhanced antioxidant activity in both leaves and stems compared to facility‐grown plants. Integrated metabolomics, antioxidant assays, and network pharmacology identified Denbinobin as a key multi‐target antioxidant compound ...
Chuyun Guan, Yixin Tang, Qiaoxian Yu, Yanghui Shen, Ying Shi, Pan Wang, Jinping Si, Jingjing Liu   +7 more
wiley   +1 more source

Mitogen-Activated Protein Kinase-3 (MAPK3) Is the Main Target of Microsecond Pulsed Electric Field in Human Medulloblastoma. [PDF]

Asian Pac J Cancer Prev
Bahadorimonfared A, Razzaghi Z, Robati RM, Arjmand B, Ahmadi N, Asri N, Keramatinia A, Razi F, Bandarian F.   +8 more
europepmc   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Mitogen-activated protein kinase kinase 4 (MKK4) as a promising therapeutic target in liver diseases: a review. [PDF]

J Enzyme Inhib Med Chem
Liu P, Liu Y, Cheng L, Bao T, Li J, Wu J, Han J, Li T, Zhang D.   +8 more
europepmc   +1 more source

CD47 promotes mitogen-activated protein kinase and epithelial-to-mesenchymal transition molecular programs to drive prometastatic phenotypes in non-small cell lung cancer. [PDF]

Mol Oncol
Lau APY, Zhai LG, Hoshi R, Rousseau Z, Zakhary A, Wu YF, Saleeb RM, Ni H, Thu KL.   +8 more
europepmc   +1 more source

Acupuncture inhibits astrocytic hyperactivationthe p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1 signaling pathway in cerebral ischemia-reperfusion injury. [PDF]

J Tradit Chin Med
Zifeng Z, Choying WO, Hongling C, Hailiang X, Canghuan Z, Di Z, Peng Q.   +6 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source