Results 221 to 230 of about 673,597 (383)

Mitochondria and Endoplasmic Reticulum Contact Site as a Regulator of Proteostatic Stress Responses in Neurodegenerative Diseases

BioEssays, EarlyView.
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley   +1 more source

Molecular cloning and sequencing of a carp cDNA encoding mitogen-activated protein kinase kinase [PDF]

, 1994
Chang-Jen Huang, Ming‐Shyue Lee, Geen‐Dong Chang, Fore‐Lien Huang, Tung‐Bin Lo   +4 more
openalex   +1 more source

Nerve growth factor stimulates the activities of the raf-1 and the mitogen-activated protein kinases via the trk protooncogene.

, 1992
M Ohmichi, Long Pang, Stuart J. Decker, Alan R. Saltiel   +3 more
openalex   +1 more source

Isolation and characterization of mutants of human mitogen‐activated protein kinase (ERK2) [PDF]

, 1994
Indira Krishnan, Eleonora D. Kovacs, Philip M. Sass   +2 more
openalex   +1 more source

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

Molecular and Cellular Biology, 1996
J. Raingeaud, A. Whitmarsh, T. Barrett, B. Dérijard, R. Davis   +4 more
semanticscholar   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Involvement of the p38 Mitogen-activated Protein Kinase Pathway in Transforming Growth Factor-β-induced Gene Expression [PDF]

, 1999
Hiroshi Hanafusa, Jun Ninomiya‐Tsuji, Norihisa Masuyama, Michiru Nishita, Jun–ichi Fujisawa, Hiroshi Shibuyà, Kunihiro Matsumoto, Eisuke Nishida   +7 more
openalex   +1 more source

Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development [PDF]

, 1996
Julia R. Köhler, Gerald R. Fink
openalex   +1 more source

The Role of the Mitogen-Activated Protein Kinase Pathway in the Development of Laser-Induced Choroidal Neovascularization. [PDF]

Int J Mol Sci
Jang SY, Yang JY, Park JH, Kim Y, An S, Jung WH, Park JW, Han JW, Kim JH, Park HS, Lyu J, Park TK.   +11 more
europepmc   +1 more source

Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases.

, 1994
Diane Milne, David G. Campbell, F. Barry Caudwell, David W. Meek   +3 more
openalex   +1 more source