Results 11 to 20 of about 90,988 (285)

The Possible Role of the Long Non-coding RNA NORAD in Mitomycin C-Related Chemoresistance

open access: yesNamık Kemal Tıp Dergisi, 2022
Aim:Non-coding ribonucleic acid (RNA) activated by deoxyribonucleic acid (DNA) damage (NORAD) is a long non-coding RNA activated during DNA damage response.
İbrahim BOZGEYİK
doaj   +1 more source

Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism [PDF]

open access: yes, 1983
Poly(dG-dC)· poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide complexes displayed varying degrees of CD inversions, which are
Barton, Jacqueline K.   +5 more
core   +1 more source

Mitomycin C in ophthalmology

open access: yesJournal of the Scientific Society, 2012
Introduction to the use of Mitomycin C in ophthalmology was a significant development in the 1960s. Its use and application in ophthalmology has been increasing in recent years, because of its modulatory effects on wound healing.
Rekha Mudhol, N D Zingade, R S Mudhol
doaj   +1 more source

Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation [PDF]

open access: yes, 1997
Reductive activation of racemic 1,10-bis(acetoxy)-7-methoxymitosene WV15 in the presence of DNA, followed by enzymatic digestion and HPLC analysis, revealed the formation of various DNA adducts.
Duynhoven, John P.M. van   +8 more
core   +2 more sources

Mitomycin C induces apoptosis in human epidural scar fibroblasts after surgical decompression for spinal cord injury

open access: yesNeural Regeneration Research, 2017
Numerous studies have shown that topical application of mitomycin C after surgical decompression effectively reduces scar adhesion. However, the underlying mechanisms remain unclear.
Tao Sui   +5 more
doaj   +1 more source

Intraoperative injection versus sponge-applied mitomycin C during trabeculectomy: One-year study

open access: yesIndian Journal of Ophthalmology, 2020
Purpose: To determine the safety and efficacy of mitomycin C (MMC) injection versus sponge during trabeculectomy. Methods: It is a prospective analysis of patients who underwent trabeculectomy with MMC and followed up for 1 year, divided into two groups,
Devendra Maheshwari   +3 more
doaj   +1 more source

Inadvertent filtering bleb due to extracapsular cataract extraction wound reopening after mitomycin C use: a case report

open access: yesJournal of Medical Case Reports, 2023
Background  Mitomycin C has been used adjunctively in various procedures, including pterygium excision. Delayed wound healing, the long-term complication of mitomycin C, can occur several years later and may rarely cause a subsequent inadvertent ...
Phit Upaphong   +2 more
doaj   +1 more source

Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery [PDF]

open access: yes, 2016
Purpose: The purpose of this study was to compare inflammatory events and graft characteristics 1 month and 6 months after conjunctival limbal autograft (CLAU) with and without intraoperative mitomycin C (MMC).
Asaad Ammaar, Mouafk   +4 more
core   +2 more sources

No effects of mitomycin-C in primary trabeculectomies in Sweden

open access: yesSAGE Open Medicine, 2018
Aim: To evaluate the results of a long-term follow-up after two different types of surgical techniques: trabeculectomy with or without mitomycin-C. Materials and methods: This study is a retrospective chart review of patients operated on with a primary ...
Marcelo Ayala
doaj   +1 more source

Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery

open access: yesIndian Journal of Ophthalmology, 2012
Purpose: To determine the efficacy of preoperative subconjunctival injection of mitomycin C a day before surgery in the management of recurrent pterygium. Materials and Methods: Randomized comparative case series. Fifty eyes with recurrent pterygium were
Khaled S Zaky, Yasser M Khalifa
doaj   +1 more source

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