Results 41 to 50 of about 47,786 (197)

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

open access: yesAdvanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao   +6 more
wiley   +1 more source

Risk factors for the leakage of chemotherapeutic agents into systemic circulation after transcatheter arterial chemoembolization of hepatocellular carcinoma

open access: yesKaohsiung Journal of Medical Sciences, 2011
This prospective study was to investigate the possible risk factors for the leakage of chemotherapeutic agent into the systemic circulation after transcatheter arterial chemoembolization (TACE) of hepatocellular carcinoma (HCC).
Ming-Yen Hsieh   +3 more
doaj   +1 more source

Evaluation of Corneal Endothelial Cells and Morphology in Mitomycin-C Augmented Trabeculectomy

open access: yesDelhi Journal of Ophthalmology, 2020
Purpose: To evaluate the effect of Mitomycin-C (MMC) on corneal endothelial cells and morphology in Mitomycin-C augmented trabeculectomy Methods: In this study, 40 eyes of patients underwent trabeculectomy with Mitomycin-C (group 1) and 40 eyes of ...
Shalini Dhiman   +2 more
doaj   +1 more source

The frequency of sister chromatid exchange and micronuclei in evaluation of cytogenetic activity of Kombucha on human peripheral blood lymphocytes [PDF]

open access: yesArchive of Oncology, 2007
Kombucha is a refreshing beverage obtained by the fermentation of sweetened black tea with a “tea fungus” (symbiotic culture of acetic acid bacteria and yeasts). It is consumed due to its potential beneficial effects on human health.
Mrđanović Jasminka   +4 more
doaj   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

The optimal starting time of postoperative intraperitoneal mitomycin-C therapy with preserved intestinal wound healing

open access: yesBMC Cancer, 2005
Background There is controversy about the effect of the timing of intraperitoneal administration of chemotherapeutic agents on the healing of intestinal anastomosis.
Bolukbas Fusun F   +4 more
doaj   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

open access: yesAdvanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang   +9 more
wiley   +1 more source

Diminishing the side effect of mitomycin C by using pH-sensitive liposomes: in vitro characterization and in vivo pharmacokinetics

open access: yesDrug Design, Development and Therapy, 2018
Yi-Ping Fang,1,2 Pei-Yu Hu,1 Yaw-Bin Huang1,3 1School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, 2Department of Medical Research, Kaohsiung Medical University Hospital, 3Center for Stem Cell Research, Kaohsiung Medical University ...
Fang YP, Hu PY, Huang YB
doaj  

Focal Urethral Stricturing Following Intraurethral Mitomycin-C Gel and the Use of a Penile Clamp

open access: yesCase Reports in Urology, 2012
We present a case of a 51-year-old gentleman, previously diagnosed with high-grade superficial transitional cell carcinoma of the bladder and treated with intravesical mitomycin C and BCG, who developed serial recurrences in the prostatic urethra.
Richard F. J. Stanford   +1 more
doaj   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

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