Results 71 to 80 of about 14,552,787 (242)

Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C

open access: yes, 2007
The modern era of targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific target. Previous attempts to forecast tumour response to conventional chemotherapeutics based on similar principles ...
Phillips, Roger M, Volpato, Milene
core  

Natural Products as Modulators of ABC Transporters in Breast Cancer

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan   +2 more
wiley   +1 more source

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min   +3 more
wiley   +1 more source

Comparison of single-drop mitomycin C regime with other mitomycin C regimes in pterygium surgery.

open access: yesIndian Journal of Ophthalmology, 2003
Purpose: To evaluate the safety and efficacy of single-drop instillation of mitomycin C (MMC) in pterygium surgery and to compare the results with both postoperative and intraoperative application of MMC.
Gupta Ved, Saxena Tishu
doaj  

Narrow band imaging‐guided diode laser ablation in recurrent low‐grade non‐muscle‐invasive bladder cancer

open access: yesUroPrecision, EarlyView.
Abstract Background Low‐grade non‐muscle‐invasive bladder cancer (NMIBC) is characterized by high recurrence rates, resulting in repeated interventions and intensive surveillance. Office‐based transurethral laser ablation (TULA) performed under local anesthesia is a minimally invasive alternative to transurethral resection, and narrow band imaging (NBI)
Ibrahim A. Khalil   +6 more
wiley   +1 more source

Distinct Patterns of Colorectal Peritoneal Metastases at Initial and Repeat Cytoreductive Surgery

open access: yesWorld Journal of Surgery, EarlyView.
Colorectal cancer rates are continually increasing in Western countries exceeding over 3 million new cases annually. Hematogenous spread to the liver is the most common metastatic route, followed by transcoelomic dissemination to the peritoneum. Colorectal peritoneal metastases (CRPM) affect 5%–8% at the time of initial diagnosis and a further 10%–20 ...
Mina Sarofim, David L. Morris
wiley   +1 more source

Comparison between the micronucleus frequencies of kidney and gill erythrocytes in tilapia fish, following mitomycin C treatment

open access: yesGenetics and Molecular Biology, 2002
The frequencies of mitomycin C and cyclophosphamide-induced kidney and gill erythrocyte micronuclei were compared in Tilapia rendalli and Oreochromis niloticus.
Dario Palhares, Cesar Koppe Grisolia
doaj   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima   +1 more
wiley   +1 more source

Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study

open access: yesBMC Cancer, 2010
Background Mitomycin C is a chemotherapeutic agent used in the treatment of peritoneal surface malignancies, administered as hyperthermic intraperitoneal chemotherapy after cytoreductive surgery.
Sørensen Olaf   +6 more
doaj   +1 more source

Safe application of mitomycin C within the nasal cavity

open access: yes, 2011
Objective:To describe a novel technique of delivering mitomycin C safely via endoscopic sinus surgery.Case report:Mitomycin C was applied in the median frontal drainage pathway of a 44-year-old woman suffering from recalcitrant chronic frontal sinusitis.
T Gutierrez   +3 more
core   +1 more source

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