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Mitomycins syntheses: a recent update
Beilstein Journal of Organic Chemistry, 2009 Mitomycins are a class of very potent antibacterial and anti-cancer compounds having a broad activity against a range of tumours. They have been used in clinics since the 1960’s, and the challenges represented by their total synthesis have challenged ...
Jean-Christophe Andrez
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An aryl radical cyclisation approach to highly substituted oxindoles related to mitomycins
ARKIVOC, 2000 Keith Jones, John M. D. Storey
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Cytotoxicity, crosslinking and biological activity of three mitomycins [PDF]
Bioorganic Chemistry, 2022 Elise Champeil +2 more
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Structural Studies of Mitomycins. VII. Mitomycin G
Acta Crystallographica Section C Crystal Structure Communications, 1996The title compound, [1aS-(1a alpha, 8a alpha, 8b alpha)]-6-amino-1, 1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-8-methyleneazirino [2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, C15H17N3O3, is a derivative of the mitomycins, which are antitumor antibiotics. The quinone O atoms deviate significantly from the least-squares plane of the quinone ring.
N, Hirayama, H, Arai, M, Kasai
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1979
The mitomycins were first obtained in 1956 from Streptomyces caespitosus by Hata and coworkers in Japan (1, 2). The isolation involved alumina chromatography of the chloroform extracts of the concentrated aqueous filtrates of the fermentation broth. Although there were many active components in the eluted fractions, only two antibiotics, mitomycins A ...
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The mitomycins were first obtained in 1956 from Streptomyces caespitosus by Hata and coworkers in Japan (1, 2). The isolation involved alumina chromatography of the chloroform extracts of the concentrated aqueous filtrates of the fermentation broth. Although there were many active components in the eluted fractions, only two antibiotics, mitomycins A ...
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Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite Naturwissenschaftliche Abteilung: Allgemeine, Landwirtschaftliche und Technische Mikrobiologie, 1975
A Z, Abou-Zeid, A, el-Sadek, A, Yousef
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A Z, Abou-Zeid, A, el-Sadek, A, Yousef
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