Results 11 to 20 of about 49,872 (195)

Mitomycin C in Homologous Recombination Deficient Metastatic Pancreatic Cancer after Disease Progression on Platinum-Based Chemotherapy and Olaparib

Biomedicines, 2022
Recent efforts to personalize treatment with platinum-based chemotherapy and PARP inhibitors have produced promising results in homologous recombinant deficient (HRD) metastatic pancreatic cancer (MPC).
Gehan Botrus, Denise Roe, Gayle S. Jameson, Pedro Luiz Serrano Uson Junior, Ronald Lee Korn, Lana Caldwell, Taylor Bargenquast, Max Miller, Erkut Hasan Borazanci   +8 more
doaj   +1 more source

Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin

Molecules, 2021
Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for ...
Dongjin Leng, Yong Sheng, Hengyu Wang, Jianhua Wei, Yixin Ou, Zixin Deng, Linquan Bai, Qianjin Kang   +7 more
doaj   +1 more source

Multimodal kidney‐preserving approach in localised and locally advanced high‐risk upper tract urothelial carcinoma

BJUI Compass, 2022
Objectives Multimodal kidney‐preserving (MKP) strategies may be an option for patients with localised or locally advanced high‐risk upper tract urothelial carcinoma (UTUC) who have a relative contraindication for nephroureterectomy (NU).
Omar Alhalabi, Matthew T. Campbell, Lianchun Xiao, Ana C. Adriazola, Nathaniel R. Wilson, Arlene O. Siefker‐Radtke, Paul G. Corn, Amado Zurita, Eric Jonasch, Jianjun Gao, Mehrad Adibi, Ashish M. Kamat, Neema Navai, Louis L. Pisters, Colin Dinney, Surena F. Matin, Amishi Y. Shah   +16 more
doaj   +1 more source

Real world survival data of a rare malignancy: Anal cancer results in HIV negative patients from Turkey

The Turkish Journal of Gastroenterology, 2018
Background/Aims: An organ preservation approach using chemoradiotherapy has been established for anal cancer. This retrospective cohort study aimed to define the clinico-demographic characteristics and outcomes of cases of human immunodeficiency virus ...
Ece Esin, Ferah Yıldız, Şahin Laçin, Yusuf Karakaş, Melis Gültekin, Şuayib Yalçın   +5 more
doaj   +1 more source

Analysis of HepG2 cell response to a wide concentration range of mitomycin C using a multichannel quartz crystal microbalance system with a microscope

Heliyon, 2023
The morphological response of HepG2 cells to mitomycin C was analyzed using a multichannel quartz crystal microbalance system equipped with a home-built movable microscope that enables the simultaneous acquisition of cell images and measurements of eight-
Hiroshi Muramatsu, Masahiro Naka, Sae Ito, Maki Kawamura   +3 more
doaj   +1 more source

Exosomal Long Non-coding RNA HOTTIP Increases Resistance of Colorectal Cancer Cells to Mitomycin via Impairing MiR-214-Mediated Degradation of KPNA3

Frontiers in Cell and Developmental Biology, 2021
It has been reported that long non-coding RNA HOXA distal transcript antisense RNA (lncRNA HOTTIP) functions as a tumor promoter in colorectal cancer (CRC).
Xijuan Chen, Yingqiang Liu, Qinglan Zhang, Baoxing Liu, Yan Cheng, Yonglei Zhang, Yanan Sun, Junqi Liu, Hong Gen   +8 more
doaj   +1 more source

Mitomycin and 5‐fluorouracil for second‐line treatment of metastatic squamous cell carcinomas of the anal canal

Cancer Medicine, 2019
Background Metastatic squamous cell carcinomas (SCC) of the anal canal are rare and there is no international consensus on their second‐line management.
Angélique Saint, Ludovic Evesque, Alexander T. Falk, Gérard Cavaglione, Lucile Montagne, Karen Benezery, Eric Francois   +6 more
doaj   +1 more source

Mitomicina-C como inibidor de sinéquias em meatos médios nas cirurgias sinusais: resultados preliminares The use of Mitomycin-C to reduce synechia in middle meatus in sinus surgery: preliminary results

Brazilian Journal of Otorhinolaryngology, 2012
As sinéquias constituem a complicação pós-operatória mais frequente das cirurgias endoscópicas sinusais, chegando a 36% dos casos. Na tentativa de diminuir esse índice, inúmeros materiais têm sido utilizados, dentre eles a Mitomicina-C (MMC).
Wellington Yugo Yamaoka, Luís Carlos Gregório   +1 more
doaj   +1 more source

Recurrence rate and clinical outcome of amniotic membrane transplantation combined with mitomycin c in pterygium surgery: Two-year follow-up

Journal of Research in Pharmacy Practice, 2020
Objective: To evaluate the recurrence rate and outcome of pterygium surgery with amniotic membrane transplantation (AMT) and intraoperative mitomycin C (MMC).
Hasan Razmjoo, Seyed-Abolfazl Kashfi, Majid Mirmohammadkhani, Mohsen Pourazizi   +3 more
doaj   +1 more source

Curcumin improved liposomal mitomycin-induced cell toxicity in bladder cancer cell [PDF]

Nanomedicine Journal, 2018
Objective (s): This study aimed at investigation of preparation and stability study of Mitomycin and Mitomycin loaded nanoliposems and efficacy of the combination of Mitomycin -loaded nanoliposomes and Curcumin versus Mitomycin in suppressing HTB-9 and ...
Farjad Amanolahi, Ali Mohammadi, Reza Kazemi oskuee, Leila Golami, Bizhan Malaekeh-Nikouei   +4 more
doaj   +1 more source