Results 11 to 20 of about 93,319 (307)

Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism [PDF]

open access: yes, 1983
Poly(dG-dC)· poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide complexes displayed varying degrees of CD inversions, which are
Barton, Jacqueline K.   +5 more
core   +1 more source

Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation [PDF]

open access: yes, 1997
Reductive activation of racemic 1,10-bis(acetoxy)-7-methoxymitosene WV15 in the presence of DNA, followed by enzymatic digestion and HPLC analysis, revealed the formation of various DNA adducts.
Duynhoven, John P.M. van   +8 more
core   +2 more sources

Mitomycin C in ophthalmology

open access: yesJournal of the Scientific Society, 2012
Introduction to the use of Mitomycin C in ophthalmology was a significant development in the 1960s. Its use and application in ophthalmology has been increasing in recent years, because of its modulatory effects on wound healing.
Rekha Mudhol, N D Zingade, R S Mudhol
doaj   +1 more source

Intraoperative injection versus sponge-applied mitomycin C during trabeculectomy: One-year study

open access: yesIndian Journal of Ophthalmology, 2020
Purpose: To determine the safety and efficacy of mitomycin C (MMC) injection versus sponge during trabeculectomy. Methods: It is a prospective analysis of patients who underwent trabeculectomy with MMC and followed up for 1 year, divided into two groups,
Devendra Maheshwari   +3 more
doaj   +1 more source

A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]

open access: yes, 2005
Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Bernier J   +25 more
core   +1 more source

Mitomycin C induces apoptosis in human epidural scar fibroblasts after surgical decompression for spinal cord injury

open access: yesNeural Regeneration Research, 2017
Numerous studies have shown that topical application of mitomycin C after surgical decompression effectively reduces scar adhesion. However, the underlying mechanisms remain unclear.
Tao Sui   +5 more
doaj   +1 more source

Inadvertent filtering bleb due to extracapsular cataract extraction wound reopening after mitomycin C use: a case report

open access: yesJournal of Medical Case Reports, 2023
Background  Mitomycin C has been used adjunctively in various procedures, including pterygium excision. Delayed wound healing, the long-term complication of mitomycin C, can occur several years later and may rarely cause a subsequent inadvertent ...
Phit Upaphong   +2 more
doaj   +1 more source

No effects of mitomycin-C in primary trabeculectomies in Sweden

open access: yesSAGE Open Medicine, 2018
Aim: To evaluate the results of a long-term follow-up after two different types of surgical techniques: trabeculectomy with or without mitomycin-C. Materials and methods: This study is a retrospective chart review of patients operated on with a primary ...
Marcelo Ayala
doaj   +1 more source

Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery

open access: yesIndian Journal of Ophthalmology, 2012
Purpose: To determine the efficacy of preoperative subconjunctival injection of mitomycin C a day before surgery in the management of recurrent pterygium. Materials and Methods: Randomized comparative case series. Fifty eyes with recurrent pterygium were
Khaled S Zaky, Yasser M Khalifa
doaj   +1 more source

Endoscopic postdilatation application of Mitomycin C in children with resistant esophageal strictures [PDF]

open access: yesKorean Journal of Pediatrics, 2019
Background The esophagus is the most common part of gastrointestinal (GI) tract at the risk of stricture. Benign disorders are the leading causes of narrowing.
Yasser K. Rashed, Mohamed El-Guindi
doaj   +1 more source

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