Results 181 to 190 of about 13,073 (205)
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Mitomycin C (z.B. Mitomycin C „Kyowa“)
2006aufgrund zahlreicher Berichte uber Nekrosen wird Mitomycin C als gewebsnekrotisierend ...
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Approaches to the mitomycins. Photochemistry of aminoquinones
The Journal of Organic Chemistry, 1977Xylochinon (I) liefert unter hoher Verdunnung mit Pyrrolidin (II) das Addukt (III), dessen Photolyse zum Cyclisierungsprodukt (IV) fuhrt.
Smith Sp, Falci Kj, Franck Rw
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Reductive Activation of Mitomycin A by Thiols
Organic Letters, 2001[reaction: see text]. Mitomycin C is unchanged upon exposure to thiols under physiological conditions. Its more toxic variant, mitomycin A (MA), undergoes elimination of methanol to give a variety of mitosene derivatives, diagnostic of its activation to a reactive electrophile. Evidence is presented for a novel reductive mechanism, characterized by the
Manuel M. Paz, Maria Tomasz
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Mitomycins and the bleaching of Euglena gracilis
Archiv für Mikrobiologie, 1969The effects of some mitomycin antibiotics on the chloroplast system of Euglena gracilis were studied. Only those derivatives which contained an alkyl group on the aziridine nitrogen were effective bleaching agents. Thus, only N-methyl-mitomycin, porfiromycin, and mitomycin B caused a highly significant loss of chloroplasts.
J. L. Mego, L. Ebringer, A. Jurášek
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Mitomycin C extravasation injuries
Cancer, 1983Mitomycin C extravasation produces a chronic painful ulceration similar to that of adriamycin. Pain marks the extravasation of this chemotherapeutic agent when it occurs. A complaint of pain during mitomycin administration should prompt immediate cessation of infusion and regular frequent follow-up.
Ernest K. Manders, Louis C. Argenta
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Biosynthesis of the Mitomycins
1981The mitomycins and porfiromycin (Fig. 1) constitute a complex of anticancer antibiotics which are produced by Streptomyces caespitosus (Hata et al., 1956), Streptomyces ardus sp. n (DeBoer et al., 1960) Streptomyces verticillatus (Lefemine etal., 1962) and Streptomyces michiganensis (Wolf et al., 1975). Their structures have been determined by chemical,
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A Synthetic Approach to the Mitomycins
HETEROCYCLES, 1978AbstractDie Chinone (I) reagieren unter Bestrahlung zu den Hydrochinonen (II), welche zu den Chinonen (III) oxidiert werden können.
M. Akiba, Y. Kosugi, Toyozo Takada
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Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite Naturwissenschaftliche Abteilung: Allgemeine, Landwirtschaftliche und Technische Mikrobiologie, 1975
A Z, Abou-Zeid, A, el-Sadek, A, Yousef
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A Z, Abou-Zeid, A, el-Sadek, A, Yousef
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